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Isotretinoin Side Effects Years Later

isotretinoin side effects years later

Introduction

Accutane is a brand-name version of the drug isotretinoin. The brand is no longer available in the United States. However, the generic version of isotretinoin and other brand-name versions, such as Absorica, are still available.

Isotretinoin is used to treat a type of severe acne called nodular acne. Nodular acne causes red, swollen, tender lumps to form in the skin. If untreated, nodular acne can lead to permanent scarring.

Your doctor will only prescribe isotretinoin when other treatments, including antibiotics, haven’t helped your nodular acne. While isotretinoin can help treat nodular acne, it can also cause many side effects. Som

Proper Use

Isotretinoin comes with a patient information form and Medication Guide. It is very important that you read and understand this information. Be sure to carefully follow these instructions and ask your doctor if you have any questions.

Women of reproductive age must sign up for a pregnancy risk program called iPLEDGE™ in order to receive their isotretinoin prescription each month. You can sign up on the internet (www.ipledge.com) or by telephone (1-866-495-0654). Be sure to ask your doctor if you have any questions about this program. It is very important that you understand and follow all of the requirements. You will not get another prescription unless you follow the instructions for the program.

Swallow the capsule whole with a full glass (8 ounces) of water or other liquid. Accutane® and its generic products should be taken with food. Absorica® may be taken with or without food. Do not crush, break, chew, or suck the capsule.

It is very important that you not share this medicine with anyone else because of the risk of birth defects and other serious side effects.

Absorica® oral capsules should not be substituted with other forms of isotretinoin (eg, Accutane®). Different brands may not work the same way. If you refill your medicine and it looks different, check with your pharmacist.

Precautions

Before starting Isotretinoin treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.

Do not take vitamin A supplements. Vitamin A in high doses has many of the same side effects as Isotretinoin. Taking both together may increase your chance of getting side effects.

Do not receive any kind of immunization or vaccination without your doctor's approval while taking Isotretinoin.

Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category X (Isotretinoin may cause fetal harm when given to a pregnant woman. Isotretinoin must not be given to a pregnant woman or a woman who intends to become pregnant. If a woman becomes pregnant while taking Isotretinoin, the medication must be stopped immediately and the woman given appropriate counseling).

Because of the extremely high risk that a deformed infant can result if pregnancy occurs while taking Isotretinoin in any amount even for short periods of time, for both men and women: Do not conceive a child (get pregnant) while taking Isotretinoin. Two methods of effective contraception are recommended for women of childbearing potential, unless absolute abstinence is the chosen method. Discuss with your doctor when you may safely become pregnant or conceive a child after therapy.

Do not breast feed while taking Isotretinoin.

Do not donate blood while on isotretinoin and for 1 month after stopping this drug.

Do not take tetracycline antibiotics (doxycycline, tetracycline, minocycline, demeclocycline) while on isotretinoin.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

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