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Isotretinoin India

isotretinoin india

Side Effects of Isotretinoin 20mg

Dryness Of Mucous Membranes, Dryness Of Skin With Scaling, Fragility, Erythema, Cheilitis, Pruritus, Epistaxis, Conjunctivitis, Dry Sore Mouth And Palmo-Plantar Exfoliation. Corneal Opacities, Dry Eyes, Visual Disturbances, Skeletal Hyperostosis And Musculoskeletal Symptoms. Elevation Of Serum Triglycerides, LFTs, ESR And Blood Glucose. Hair Thinning, Photosensitivity, Changes In Skin Pigmentation, Paronychia. GI Disturbances, Hepatitis. Headache, Drowsiness, Sweating, Mood Changes, Psychotic Symptoms, Depression, Suicidal Tendencies, Benign Intracranial Hypertension, Seizures. Vasculitis, Hypersensitivity Reactions, IBS. Potentially Fatal: Anaphylaxis. Haemorrhagic Pancreatitis.

Mechanism of Action of Isotretinoin 20mg

Isotretinoin Is A Synthetic Retinoid Which Reduces Sebaceous Gland Size And Sebum Production. It Also Regulates Cell Proliferation And Differentiation. Absorption: Low Oral Bioavailability. Peak Plasma Concentrations In 1-4 Hr (Oral). Distribution: Protein-Binding: 99.9%, Mainly To Albumin. Metabolism: Hepatic, Via CYP450 Isoenzyme Pathway. Excretion: Via Urine And Faeces.

Irresponsible prescription of Sotret in India

Someone we know was prescribed Sotret even after they repeatedly told a big-name dermatologist that they had a history of depression. Perhaps read this Sotret Ranbaxy medication guide to get a better idea of how Sotret can wreck havoc on a person’s mental state.

Medical literature says that Accutane / Sotret should only be used as a last resort in acne treatment. Still, you come across accounts of men and women being prescribed Sotret by their dermatologists without exhausting other options first.

On the Internet, you find Indian dermatologists prescribing Sotret in online chat rooms calling it “just a vitamin a supplement” with “no side effects”.

Doctors may be the best judge, but they are not the best informers. It is not about how dangerous Sotret is. It is about how dermatologists don’t care enough to inform patients about the possible side effects of Sotret. Or take into account a patient’s mental and physical constitution.

We cannot label all dermatologists as irresponsible, but many are too rushed to care.

In countries like the U.S. and U.K., you can only get Accutane through prescription and even that process is carefully controlled. In India, it is generally a matter of walking up to your nearest medical store.


Use Accutane as directed by your doctor.

  • Take Accutane by mouth with food.
  • Swallow the capsule with a full glass of water or other liquid. Do not break, crush, chew, or suck on the capsule before swallowing. This will help prevent the medication inside the capsule from irritating your throat.
  • For best results, take Accutane regularly. Taking Accutane at the same time each day will help you remember to take it.
  • If you miss a dose of Accutane, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
  • Ask your health care provider any questions you may have about how to use Accutane.


Store Accutane at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Accutane out of the reach of children and away from pets.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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