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Is Topiramate Used For Weight Loss

is topiramate used for weight loss

Topamax (Topiramate)?

Topamax is the brand name of topiramate, an anticonvulsant drug used to prevent seizures and reduce the frequency of migraines.

While its exact mechanism of action is unknown, studies suggest Topamax might alter the production or action of neurotransmitters in the brain, suppressing the abnormal activity of the nerves in the brain that cause seizures or preventing the abnormal activity from spreading to other nerves. Other research has suggested that it might suppress the nerves directly, thereby making them less likely to fire.

Warnings

In a small number of people, Topamax has been known to cause suicidal thoughts or actions, new or worse anxiety, irritability, and depression as well as feelings of agitation, restlessness, aggression, panic attacks, mania, and insomnia.

This medication could also cause sleepiness and impact your ability to think, causing confusion and problems with concentration, attention, memory, and speech.

Topamax For Weight Loss, You're Going Off-Label

The drug is approved by the Food and Drug Administration as being safe for treating seizures and migraines—but it’s not a drug that weight-loss physicians would usually recommend, says Peter LePort, M.D., a bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, Calif. “It’s a serious medication,” he says. “Whether it’s safe to use for dieting is really up in the air right now.”

Conclusion

The evidence of a strong weight-reducing potential of topiramate is indisputable and clinically significant. Topiramate could be considered in the treatment of bipolar patients who are overweight, or whose concerns about weight gain compromise their compliance with long-term prophylactic medication. So far there is no evidence that topiramate has anti-manic effect and it should not be used as monotherapy.

Precautions

Before taking topiramate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain eye problem (narrow angle glaucoma), kidney problems (such as kidney stones), liver problems, mental/mood problems (such as depression, thoughts of suicide), lung/breathing problems, a certain metabolic imbalance (metabolic acidosis), long-term diarrhea, a diet high in fat and low in carbohydrates (ketogenic diet), brittle bones (osteoporosis).

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center residents can call a provincial poison control center. Symptoms of overdose may include: severe drowsiness, loss of consciousness.

Laboratory and/or medical tests (such as eye exams, bicarbonate blood level) should be performed to monitor your progress and check for side effects.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is within 6 hours of your next dose, skip themissed dose. Take your next dose at the regular time. Do not double the dose to catch up. If you miss more than one dose, call your doctor for advice.

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