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Insulin glargine

Insulin glargine

What is insulin glargine?

Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin glargine is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours.

Insulin glargine is used to improve blood sugar control in adults and children with diabetes mellitus. Insulin glargine is used to treat type 1 or type 2 diabetes in adults, and type 1 diabetes children who are at least 6 years old.

Lantus (Insulin Glargine) Side Effects

Using too much of the medication can result in low blood sugar, which may cause the following symptoms:

  • Chills
  • Cold sweats
  • Blurred vision
  • Dizziness or drowsiness
  • Shaking
  • Fast heartbeat
  • Weakness
  • Tingling of the hands/feet
  • Hunger


Insulin glargine is used with a proper diet and exercise program to control high blood sugar in people with diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

A product that may interact with this drug is: rosiglitazone.

Dosage Forms And Strengths

Injection: 100 units per mL of insulin glargine. LANTUS is available as:

  • 10 mL vial
  • 3 mL SoloStar prefilled pen

Lantus and Other Drug Interactions

When you are taking Lantus, it is especially important that your healthcare professional know if you are taking metreleptin ( Myalept). Using Lantus with metreleptin is usually not recommended, but may be required. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of them.

Using Lantus with any of the following medicines may cause an increased risk of certain side effects. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Iproniazid (Marsilid)
  • Isocarboxazid (Marplan)
  • Linezolid (Zyvox)
  • Methylene Blue (Urolene Blue)
  • Moclobemide (Aurorix)
  • Nialamide (Niamid)


LANTUS should not be stored in the freezer and should not be allowed to freeze. Discard LANTUS if it has been frozen. Protect LANTUS from direct heat and light