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Imatinib Side Effects

imatinib side effects

What Gleevec Is Used For

Newly diagnosed adult and pediatric patients with Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML) in chronic phase.

Ph+ CML in blast crisis, accelerated phase, or chronic phase after failure of interferon-alpha therapy.

Adult patients with relapsed or refractory Philadelphia chromosome + acute lymphoblastic leukemia (Ph+ ALL).

Adult patients with myelodysplastic/myeloproliferative diseases (MDS/MPD) associated with PDGFR gene rearrangements.

Gastrointestinal stromal tumors that are C-kit positive.

How Gleevec Is Given

Gleevec is a pill, taken by mouth, once or twice daily.

Gleevec should be taken with a large glass of water, after a meal.

The amount of Gleevec that you will receive depends on many factors, including your general health or other health problems, and the type of cancer or condition being treated.  Your doctor will determine your dose and schedule.

When not to use?

Contraindications of Imatinib 400 mg Tablet

Allergy

This medicine is not recommended for use in patients with a known allergy to imatinib or any other inactive ingredients present along with it.

Side Effects

Important things to remember about the side effects of Gleevec:

  • Most people do not experience all of the side effects listed.
  • Side effects are often predictable in terms of their onset and duration.
  • Side effects are almost always reversible and will go away after treatment is complete.
  • There are many options to help minimize or prevent side effects.
  • There is no relationship between the presence or severity of side effects and the effectiveness of the medication.
  • The side effects of Gleevec and their severity depend on how much of the drug is given.  In other words, high doses may produce more severe side effects.
  • The following side effects are common (occurring in greater than 30%) for patients taking Gleevec:

Low blood counts. ...

  • Nausea and vomiting.
  • Edema (swelling of the face, feet, hands)
  • Muscle cramps and bone pain.
  • Diarrhea.
  • Hemorrhage (see bleeding problems)
  • Skin rash (see skin reactions)
  • Fever.

Precautions

 Imatinib can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.

Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).

Dosage

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped. Contact your doctor for further instructions if you miss more than one scheduled dose of this medicine.

Overdose

Contact your doctor immediately if an overdose with this medicine is suspected. Symptoms may include nausea, vomiting, diarrhea, skin allergies, tiredness, fever, etc.

Know More About This Medicine and Buy Now : MedyPharma.com

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