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Imatinib Generic

imatinib generic


As you may have heard, a generic form of GLEEVEC may become available soon. What this means is that a pharmacy will be allowed to switch your current branded GLEEVEC medication to a generic formulation. The generic may appear differently from branded GLEEVEC in characteristics such as pill shape, size, and color. Even though the generic pill may appear different, the FDA requires that generic medications contain the same active ingredient as the brand name, and that they function comparably in your body.


A drug that is comparable to a brand/reference listed drug product in dosage, form, strength, route of administration, quality and performance characteristics, and intended use.

In February 2016, a generic version of imatinib (Gleevec), the groundbreaking tyrosine kinase inhibitor, was made available in the United States. Imatinib has ushered in a new era of targeted oncology drug development, but has also been credited with creating a new era of drug pricing.

Two Generic Versions of Imatinib Launched -- but Will Prices Drop?

Teva Pharmaceutical Industries has announced the launch of a generic version of imatinib mesylate, which is currently manufactured by Novartis and is sold under the brand name Gleevec.

Their generic product will be sold in 100-mg and 400-mg versions and will be available for all of the indications for which the drug has been approved by the US Food and Drug Administration (FDA).


Tablets (scored): 100 mg and 400 mg


Patients are to take Imatinib Mesylate Tablets exactly as directed by their doctor. For complete details about dosage and administration, please refer the Dosage and Administration section of the Full Prescribing Information.


Edema and severe fluid retention have occurred. Weigh patients regularly and manage unexpected rapid weight gain by drug interruption and diuretics.

Cytopenias, particularly anemia, neutropenia, and thrombocytopenia, have occurred. Manage with dose reduction or dose interruption and in rare cases discontinuation of treatment. Perform complete blood counts weekly for the first month, biweekly for the second month, and periodically thereafter.

Severe congestive heart failure and left ventricular dysfunction have been reported, particularly in patients with comorbidities and risk factors. Patients with cardiac disease or risk factors for cardiac failure should be monitored and treated.

Side Effects

ell your doctor if you have serious side effects of Gleevec including:

  • severe blistering skin rashes,
  • yellowing skin and eyes (jaundice),
  • gastrointestinal bleeding,
  • weakness with shortness of breath,
  • severe headaches,
  • swelling,
  • severe flu-like symptoms.
  • easy bruising or bleeding,
  • nausea,
  • stomach pain or upset,
  • vomiting,
  • diarrhea,
  • gas,
  • headache
  • muscle or joint pain,
  • muscle cramps,
  • feeling tired,
  • dizziness,
  • blurred vision,
  • drowsiness,
  • skin rash,
  • flu-like symptoms,
  • stuffy nose, or
  • sinus pain.


Be on the lookout. While your pharmacist should tell you if your drug has been switched to the generic, they may not, so be aware of things that may indicate you have received the generic, such as different packaging. If you do receive a generic version of Imatinib, be sure to tell your doctor so that they can be aware should you experience new side effects or a loss of response.

Keep it the same. Be aware of which generic version you receive – does it come from Apotex, Teva or Cobalt? Make sure you receive the same generic every time you refill your prescription.


In conclusion, imatib (copy) is effective and safe in treating patients with CML in chronic phase and proves to have a durable outcome. To our knowledge this is the first study reporting the response to imatib (copy) in a Algerian population.

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