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Ibrutinib

Ibrutinib

Buy Ibrutinib

Ibrutinib is a prescription medication used as an inhibitor of Bruton's tyrosine kinase (BTK) used to treat patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. Ibrutinib is available under the following different brand names: Imbruvica           

WHAT IS IBRUTINIB AND HOW DOES IT WORK?

Ibrutinib is a prescription medication used as an inhibitor of Bruton's tyrosine kinase (BTK) used to treat patients with mantle cell lymphoma (MCL) who have received at least one prior therapy.

Ibrutinib is available under the following different brand names: Imbruvica.

Dosages of Ibrutinib:

Adult Dosages:

Capsule

  • 140 mg

Dosage Considerations

Indications for mantle cell lymphoma and marginal cell lymphoma is based on overall response rate (both received accelerated approval from the FDA); an improvement in survival or disease-related symptoms has not been established

Available via a limited distributed system from specialty pharmacies

How Ibrutinib Is Given:

  • Ibrutinib is a capsule, taken by mouth once daily. You may take 1-4 capsules at once depending on your prescribed dose.
  • Take ibrutinib at approximately the same time each day.
  • Take ibrutinib exactly as prescribed.
  • Swallow ibrutinib capsules whole with at least 8 ounces of water. Do not crush, open, chew or dissolve capsules.
  • Do not change your dose or stop ibrutinib unless your health care provider tells you to.
  • If you miss a dose of irbrutinib, it should be taken as soon as possible on the same day with return to the normal schedule the following day. Do not take extra capsules of ibrutinib to make up the next dose.
  • Do not take more than 1 dose of ibrutinib at one time. Call your health care provider and go to the emergency room right away if you take too much.
  • Store at room temperature (68° F to 77° F); keep medication in original bottle; protect from high humidity, moisture and light.

WHAT ARE SIDE EFFECTS ASSOCIATED WITH USING IBRUTINIB?

Common side effects of ibrutinib include:

  • abdominal pain
  • anemia
  • anxiety
  • bruising
  • chills
  • constipation
  • cough

Precautions:

Do not drink grapefruit juice, eat grapefruit or eat Seville oranges (often used in marmalades) while you are taking ibrutinib. These products may increase the amount of ibrutinib in your blood.

Before starting ibrutinib treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).

While taking ibrutinib, do not receive any kind of immunization or vaccination without your doctor’s approval.

Limit your time in the sun. Ibrutinib can make your skin sensitive to sunlight. A severe sunburn, rash or worsening acne can occur with too much exposure. Remember to use sunscreen and wear a hat and clothes that cover as much of your skin as possible while taking ibrutinib

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