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Ibandronic Acid

Ibandronic Acid


Ibandronate is one of the newest oral bisphosphonates on the market. As a result, relevant data on the drug are substantially sparser than for alendronate and risedronate. To this end, there have been no clinical trials to date investigating ibandronate’s effects in the male skeleton; nor has there been enough data in either sex to show statistically significant reductions in hip fracture risk with the use of ibandronate. Vertebral fracture data have been described. The Ibandronate Osteoporosis Vertebral Fracture trial in North America and Europe (BONE) showed that daily ibandronate effectively improved vertebral BMD by 5% and reduced the risk of new vertebral fractures by 62% in postmenopausal women with one or more pre-existing vertebral fractures.

Side effects of ibandronic acid (Bondronat)

Find out about the side effects of the bisphosphonate drug ibandronic acid.

Tell your doctor or nurse if you have any side effects so they can help you manage them. Your nurse will give you a contact number to ring if you have any questions or problems. If in doubt, call them.

The side effects may be different if you are having ibandronic acid with other cancer treatments.

Common side effects

  • Feeling sick
  • Indigestion
  • Tiredness and weakness
  • Irritation of food pipe (oesophagus)
  • Low levels of calcium in your blood (hypocalcaemia)
  • Bone pain

How to take ibandronic acid

Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about ibandronic acid, and it will also provide you with a full list of the side-effects which you could experience from taking it. Not all brands of tablet are used to treat each of the conditions mentioned in this leaflet.

If you are taking 50 mg tablets (for bone problems in breast cancer): the usual dose is one 50 mg tablet each morning, although you may be asked to take it less frequently than this if you have any problems with the way your kidneys work. If on any day you forget to take a tablet, do not take the tablet at another time - just take the tablet due on the following day as usual. Do not take two tablets on the same day to make up for a missed dose.

Dosage Information

The recommended dose of BONIVA Injection for the treatment of postmenopausal osteoporosis is 3 mg every 3 months administered intravenously over a period of 15 to 30 seconds. Do not administer more frequently than once every 3 months.

Dosing After Missed Dose

If the dose is missed, administer as soon as it can be re-scheduled. Thereafter, BONIVA Injection should be scheduled every 3 months from the date of the last injection.

How it works

Ibandronic acid strengthens the bone and stops the bone from breaking down.

How to store ibandronic acid

Keep all medicines out of the reach and sight of children.

Store in a cool, dry place, away from direct heat and light.