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Hydroxyurea Wiki

hydroxyurea wiki

Hydroxycarbamide, also known as hydroxyurea wiki, is a medication used in sickle-cell disease, chronic myelogenous leukemia, cervical cancer, and polycythemia vera.[1][2] In sickle-cell disease it decreases the number of attacks.[1] It is taken by mouth.[1]

Common side effects include bone marrow suppression, fevers, loss of appetite, psychiatric problems, shortness of breath, and headaches.[1][2] There is also concern that it increases the risk of later cancers.[1] Use during pregnancy is typically harmful to the baby.[1] Hydroxycarbamide is in the antineoplastic family of medications. It is believed to work by blocking the making of DNA.

hydroxyurea wiki Usage

Always follow your doctor’s instructions carefully when taking hydroxyurea wiki capsules or any prescription medication.

The usual dose of hydroxyurea wiki may range from as few as one to several capsules per day. hydroxyurea wiki is usually taken once a day. You should try to take it at the same time each day. Your doctor will determine the proper starting dose of hydroxyurea wiki for you based on your weight and blood count. The dose will then be increased slowly to your maximum tolerated dose (maximum dose that does NOT produce severely low blood counts).Your doctor should measure your blood counts every two weeks after you begin treatment with hydroxyurea. Depending on the results, your dosage may be adjusted or the drug may be stopped for a while.

How hydroxyurea wiki Works:

Cancerous tumors are characterized by cell division, which is no longer controlled as it is in normal tissue.   "Normal" cells stop dividing when they come into contact with like cells, a mechanism known as contact inhibition.  Cancerous cells lose this ability.  Cancer cells no longer have the normal checks and balances in place that control and limit cell division.  The process of cell division, whether normal or cancerous cells, is through the cell cycle.  The cell cycle goes from the resting phase, through active growing phases, and then to mitosis (division).

The ability of chemotherapy to kill cancer cells depends on its ability to halt cell division.  Usually, the drugs work by damaging the RNA or DNA that tells the cell how to copy itself in division.  If the cells are unable to divide, they die.  The faster the cells are dividing, the more likely it is that chemotherapy will kill the cells, causing the tumor to shrink.  They also induce cell suicide (self-death or apoptosis).

Side Effects of hydroxyurea wiki

As with other medicines, hydroxyurea wiki may cause unwanted effects, although it is not always possible to tell whether such effects are caused by hydroxyurea, another medication you may be taking, or your sickle cell anemia. Any side effects or unusual symptoms that you experience should be reported to your doctor, particularly if they persist or are troublesome.

The most serious side effects of hydroxyurea wiki involve the blood and may include severely low white blood cell counts (leukopenia, neutropenia), which can decrease your resistance to infections, severely low red blood cell counts (anemia), or severely low platelet counts (thrombocytopenia), which can cause bleeding. Almost all patients who received hydroxyurea in clinical studies needed to have their medication stopped for a time to allow their low blood counts to return to acceptable levels.

hydroxyurea wiki Interactions

Some other medications can increase your risk of experiencing serious side effects from hydroxyurea. While you are taking hydroxyurea capsules, you should inform your doctor of all prescription and over-the-counter medicines that you are taking.

hydroxyurea wiki Precautions

hydroxyurea wikiare used to treat sickle cell anemia in adults. hydroxyurea wikireduces the frequency of painful crises and reduces the need for blood transfusions.

It is VERY IMPORTANT that you have regular blood counts so that your doctor can decrease or increase the hydroxyurea dose as needed to avoid serious complications.

The most serious side effects of hydroxyurea involve the blood and may include severely low white blood cell counts (leukopenia, neutropenia), which can decrease your resistance to infections,

hydroxyurea wiki Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

actual or ideal weight, whichever is less

how you respond to this medication

your blood counts

hydroxyurea wiki Overdose

If you accidentally take an overdose of hydroxyurea wiki capsules, seek medical attention immediately. Contact your doctor, local Poison Control Center, or emergency room.

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