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Hydroxyurea 500 Mg

hydroxyurea 500 mg

Hydroxyurea is a prescription drug sold under the brand name Hydrea. It's used to treat psoriasis, chronic myelogenous leukemia (a cancer of the white blood cells), ovarian cancer, melanoma (a form of skin cancer), and certain head and neck cancers.

What is hydroxyurea 500 mg?

hydroxyurea 500 mg is a prescription drug. It comes in two forms: a capsule and a tablet. You take both forms by mouth.

Hydroxyurea oral capsule is available as the brand-name drugs Hydrea and Droxia. Hydrea is also available as a generic drug. Droxia is not. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.

Hydroxyurea may be used as part of a combination therapy. This means you may need to take it with other medications.

Why it's used

hydroxyurea 500 mg is used to treat myeloid leukemia and head and neck cancers. It prevents cancer cells from growing. It’s also used to treat sickle cell disease.


This medication is used by people with sickle cell anemia to reduce the number of painful crises caused by the disease and to reduce the need for blood transfusions. Some brands are also used to treat certain types of cancer (such as chronic myelogenous leukemia, squamous cell carcinomas).

How it works

hydroxyurea 500 mg belongs to a class of drugs called antimetabolites. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

In people with cancer, hydroxyurea acts as a substitute for some parts that the cancer cells need to grow. Cancer cells take in hydroxyurea, which stops the cancer cell from growing. Cancer cells grow more rapidly than normal cells, so they are more affected by the drug.

Who should NOT take this medication?

Do not take this medication if you:

  • are allergic to hydroxyurea or any ingredients of the medication
  • have a very low platelet count
  • have a very low white blood cell count
  • have severe anemia

Side Effects

More Common

  • Chills
  • cough
  • fever
  • hoarseness
  • lower back or side pain
  • painful or difficult urination
  • Less Common
  • Black, tarry stools
  • blackening of the fingernails and toenails
  • blood in the urine or stools
  • pinpoint red spots on the skin
  • sores in the mouth and on the lips

What form(s) does this medication come in?

Each capsule with opaque green cap and opaque pink body printed with "BMS 303" in black ink on both body and cap, contains 500 mg hydroxyurea. Nonmedicinal ingredients: citric acid, dibasic sodium phosphate, lactose, and magnesium stearate.

How should I use this medication?

The recommended dose of hydroxyurea 500 mg varies according to the specific condition being treated, the response to therapy, the other medications used, whether radiation is being used at the same time, the stage of condition, and the body weight of the recipient.


hydroxyurea 500 mg comes as a capsule to take by mouth. Your dose will be based on your weight, medical condition, and response to treatment.The medicine is usually taken once a day.When hydroxyurea is used to treat certain types of cancer, it's sometimes taken once every three days.Try to take the drug around the same time each day.Don't crush, chew, or split the capsules. Swallow them whole.


  • Symptoms of a hydroxyurea overdose may include:
  • Pain, redness, swelling, or scaling on the hands and feet
  • Sores in the mouth and throat
  • Darkening of the skin
  • If you suspect an overdose, contact a poison control center or emergency room immediately.
  • You can get in touch with a poison control center at 800-222-1222.

Missed Dose of hydroxyurea 500 mg

  • If you miss a dose of hydroxyurea 500 mg, take it as soon as you remember.
  • But skip the missed dose if it's almost time for your next scheduled dose.
  • Don't take extra medicine to make up for a missed dose.

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