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Human Chorionic Gonadotropin

Human Chorionic Gonadotropin

What is Human chorionic gonadotropin?

Human chorionic gonadotropin (hCG) is a hormone produced by the placenta after implantation.[1][2] The presence of hCG is detected in some pregnancy tests (HCG pregnancy strip tests). Some cancerous tumors produce this hormone; therefore, elevated levels measured when the patient is not pregnant may lead to a cancer diagnosis and, if high enough, paraneoplastic syndromes, however, it is not known whether this production is a contributing cause, or an effect of carcinogenesis. The pituitary analog of hCG, known as luteinizing hormone (LH), is produced in the pituitary gland of males and females of all ages.

Dosage

What happens if I miss a dose?

Contact your doctor if you miss a dose of HCG.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of HCG is not expected to produce life-threatening symptoms.

Side Effect

Major and Minor HCG Side Effect

  • severe pelvic pain;
  • swelling of the hands or legs;
  • stomach pain and swelling;
  • shortness of breath;
  • weight gain;
  • diarrhea;
  • nausea or vomiting
  • urinating less than normal
  • headache;
  • feeling restless or irritable;
  • mild swelling or water weight gain;
  • depression;
  • breast tenderness or swelling
  • pain, swelling, or irritation where the injection is given

What other drugs will affect HCG?

There may be other drugs that can interact with HCG. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

What happens if I have too little human chorionic gonadotrophin?

Low levels of human chorionic gonadotrophin can indicate a failing pregnancy. Reduced levels of human chorionic gonadotrophin are often observed in ectopic pregnancies (where the embryo implants outside of the uterus) or in miscarriages.

HCG and Weight Loss

Although a prescription drug, HCG pills and liquid are sometimes purchased as a weight-loss supplement.

Since the FDA has not approved HCG for weight loss or over-the-counter (OTC) use, its sale is illegal, and any purported benefit of HCG in weight loss remains controversial.

The manufacturer of Pregnyl clearly states in its package insert that HCG has no proven benefit in weight loss, appetite decrease, or change in body-fat composition.

 

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