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How Long Does It Take Naproxen To Work

How Long Does It Take Naproxen To Work


Naproxen is a non-steroidal anti-inflammatory medication. It is prescribed to relieve inflammation, swelling, stiffness and is also an effective pain killer. It is of particular use in arthritic conditions, menstrual pain and discomfort, acute attacks of gout and for broad spectrum pain relief. Naproxen can also be used to reduce fever.

This medication does not cure the underlying condition responsible for pain, fever or inflammation, but simply keeps the symptoms under control.

At moderate doses - not exceeding 1 g per day - naproxen appear to have fewer gastrointestinal side effects than aspirin and many other non-steroidal anti-inflammatory drugs. It may however still cause gastrointestinal irritation and should be used with caution if you have a stomach ulcer or related disease.

This risk increases the longer you take this medication, or if you are also taking corticosteroid medications such as prednisone, anticoagulants (blood thinning medication) such as warfarin, or if you smoke or consume alcohol while being treated with naproxen. To reduce this, it is advised to take this medication with food.

How does naproxen work?

Naproxen blocks the production of chemicals in the body that is responsible for pain, fever, swelling and inflammation.

Drug schedule: Schedule 2, 3

Available as: Naproxen is available as tablets and suppositories.

What does it do? Naproxen reduces pain, fever and inflammation.

Overdose risk: Medium

Dependence risk: Low

Is naproxen available as a generic ? Yes

Is naproxen available on prescription only? No

User information

Onset of effect: Within 60 minutes

Duration of action: Up to 12 hours

Dietary advice: Naproxen should be taken with a meal to minimise gastrointestinal irritation.

Stopping this medicine: Unless your doctor has prescribed Naproxen for long-term use, it can be safely stopped when no longer needed.

Prolonged use: The likelihood of adverse effects increases with prolonged use. Your doctor may perform periodic liver and kidney function tests, while also examining you for possible gastrointestinal damage.

Naproxen or naproxen sodium is a type of drug called a non-steroidal anti-inflammatory drug (NSAID). It works by stopping the production of compounds called prostaglandins in the body, which have a number of effects, including to cause inflammation.

As a result, naproxen can help to reduce pain and inflammation by stopping the production of prostaglandins. This is why it is usually used to relieve painful inflammatory conditions, such as arthritis. It is also commonly used to help relieve period pain in women.

Naproxen works by inhibiting COX-1 and COX-2, which are needed to produce the different prostaglandins in your body. You have many different types of prostaglandins in your body, and there are some in almost every tissue of your body. They each have different effects, such as to cause:

  • the tissues in your body to become inflamed
  • your blood vessels to relax and widen
  • the platelets in your blood to come together to form a clot

How to take it

Naproxen on prescription comes as 2 different tablets - effervescent and gastro-resistant tablets.

Effervescent tablets are dissolved in water before you take them.

Gastro-resistant tablets have a coating to protect them from being broken down by the acid in your stomach. Instead, the medicine is released further down the gut in your intestine.

If you take gastro-resistant tablets, swallow them whole with or after food. Don't crush or chew them.

If you take effervescent tablets, dissolve 1 to 2 tablets in a glass (150ml) of water and drink.

Doses of 3 tablets should be dissolved in 300ml. To make sure there is no medicine left, rinse the empty glass with a small amount of water and drink it. Take with or after food.

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