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Glimepiride Drug Class

glimepiride drug class

What is glimepiride?

Glimepiride is a prescription drug. It comes as an oral tablet. Glimepiride is available as the brand-name drug Amaryl and as a generic drug. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version. This drug may be used as part of a combination therapy. That means you need to take it with other drugs.

Uses

Glimepiride is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. It may also be used with other diabetes medications. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Glimepiride belongs to the class of drugs known as sulfonylureas. It lowers blood sugar by causing the release of your body's natural insulin.

How to use Glimepiride

Read the Patient Information Leaflet if available from your pharmacist before you start taking glimepiride and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with breakfast or the first main meal of the day, as directed by your doctor, usually once daily. The dosage is based on your medical condition and response to treatment.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. If you are already taking another diabetes drug (such as chlorpropamide), follow your doctor's directions carefully for stopping the old drug and starting glimepiride.

How it works

Glimepiride belongs to a class of drugs called sulfonylureas. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Glimepiride helps your pancreas to release insulin. Insulin is a chemical that your body makes to move sugar (glucose) from your bloodstream into your cells. Once the sugar enters your cells, they can use it as fuel for your body.

With type 2 diabetes, your body doesn’t make enough insulin, or it can't properly use the insulin that it makes, so the sugar stays in your bloodstream. This causes high blood sugar levels (hyperglycemia).

Serious side effects

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

severe low blood sugar (less than 35 to 40 mg/dL). Symptoms may include:

  • mood changes, such as irritability, impatience, anger, stubbornness, or sadness
  • confusion, including delirium
  • lightheadedness or dizziness
  • sleepiness
  • blurred or impaired vision
  • tingling or numbness in your lips or tongue
  • headaches
  • weakness or fatigue
  • lack of coordination
  • nightmares or crying out in your sleep
  • seizures
  • unconsciousness

Dosage

Missed Dose

The missed dose can be taken as soon as you remember. If it is time for the next dosage then the missed dose can be skipped.

Overdose

It is recommended to discontinue the medication and contact your doctor immediately if an overdose is suspected. Symptoms like dizziness, confusion, increased heartbeat, tremor and sweating after taking the medication should be reported immediately.

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