My Cart

0 Item(s): $0.00

You have no items in your shopping cart.

Doxazosin Mesylate

Doxazosin Mesylate

What is doxazosin mesylate, and how does it work?

Doxazosin is an oral drug used for treating high blood pressure and symptoms of benign prostatic hyperplasia (BPH, a noncancerous enlargement of the prostate gland). It belongs to a class of drugs called alpha-1 adrenergic blockers. Other drugs in this class include alfuzosin (Uroxatral), terazosin (Hytrin), tamsulosin (Flomax), silodosin (Rapaflo), and prazosin (Minipress). Doxazosin prevents norepinephrine that is released by nerves from binding to alpha-1 receptors on smooth muscle surrounding blood vessels and in the prostate and bladder. By blocking the effect of norepinephrine, doxazosin relaxes the smooth muscle.

Why is this medication prescribed?

Doxazosin is used in men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia or BPH), which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency. It is also used alone or in combination with other medications to treat high blood pressure. Doxazosin is in a class of medications called alpha-blockers. It relieves the symptoms of BPH by relaxing the muscles of the bladder and prostate. It lowers blood pressure by relaxing the blood vessels so that blood can flow more easily through the body.

How it works

Doxazosin belongs to a class of drugs called alpha-blockers. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Doxazosin works by blocking certain chemicals, which helps to widen blood vessels and relax muscles in your prostate and in your bladder.

Side Effect

Major and Minor doxazosin Side Effect

  • dizziness
  • lightheadedness
  • fatigue
  • tired feeling
  • drowsiness
  • headache
  • shortness of breath
  • nausea
  • runny nose
  • diarrhea
  • abdominal pain
  • swelling (edema)

Important warnings

Low blood pressure warning: Doxazosin can cause your blood pressure to become low. This may cause dizziness, lightheadedness, and vertigo when you stand up. This is most common with your first dose of medication, but it can also occur when your doctor changes your dosage. To help prevent this problem, your doctor will start you on the lowest dosage and slowly increase it.

Cataract surgery warning: Intraoperative floppy iris syndrome (IFIS) can occur during cataract surgery in people who take or have taken doxazosin. Be sure to tell your doctor if you have a cataract surgery planned.

Doxazosin and Pregnancy

It's not known whether doxazosin will harm an unborn baby. You should tell your doctor if you are pregnant or might become pregnant while taking this medication.

It's also not known whether the drug passes into breast milk or if it could harm a breastfeeding baby.