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Donepezil 10 Mg

donepezil 10 mg

What is donepezil?

Donepezil, which is sold under the brand name Aricept, is a cholinesterase inhibitor (an enzyme blocker) used to treat mild, moderate, or severe dementia in people who have Alzheimer's disease.

It improves mental functions (including attention, memory, and the ability to interact and speak with others) by preventing the naturally occurring neurotransmitters in the brain from breaking down.

It will not cure Alzheimer's or prevent the loss of mental abilities in the future.

Donepezil was approved by the Food and Drug Administration (FDA) in 1996 to treat mild to moderate Alzheimer's. Currently, donepezil is the world's best-selling Alzheimer's drug.

Why it’s used

Donepezil is used to treat dementia due to mild, moderate, and severe Alzheimer’s disease. This drug isn’t a cure for Alzheimer’s disease, but it may help slow down how quickly your symptoms progress. Symptoms of Alzheimer’s disease will get worse over time, even if you take medications such as donepezil.

How it works

Donepezil belongs to a class of drugs called acetylcholinesterase inhibitors. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

People with Alzheimer’s disease have low amounts of a chemical in the brain called acetylcholine. Low levels of this chemical can cause dementia, or problems with mental function or doing daily tasks. Donepezil works by preventing the breakdown of acetylcholine. This can help decrease the symptoms of dementia.

Less serious side effects include:

  • Loss of appetite
  • Weight loss
  • Nausea
  • Vomiting
  • Diarrhea
  • Frequent urination
  • Muscle cramps, painful and swollen joints
  • Excessive tiredness
  • Difficulty falling asleep
  • Headache, nervousness, dizziness
  • Depression, mood swings
  • Vivid dreams

More serious side effects may demand immediate emergency medical attention and include:

  • Chest pain
  • Difficulty with urination
  • Swelling of the tongue, throat, or face
  • Severe anemia
  • Slow heartbeat
  • Breathing problems
  • Fainting
  • Worsening stomach pain
  • Black or bloody stools
  • Bloody vomit
  • Seizures
  • Fever

Donepezil Warnings

For pregnant women: Donepezil is a category C pregnancy drug. That means two things:

  1. Research in animals has shown adverse effects to the fetus when the mother takes the drug.
  2. There haven’t been enough studies done in humans to be certain how the drug might affect the fetus.

Tell your doctor if you’re pregnant or plan to become pregnant. Donepezil should be used during pregnancy only if the potential benefit justifies the potential risk.

If you become pregnant while taking this drug, call your doctor right away.

For women who are breastfeeding: It isn’t known if donepezil passes into breast milk. If it does, it may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

For seniors: As you age, your organs (such as your liver and kidneys) may not work as well as they did when you were younger. More of this drug may stay in your body longer, putting you at risk of increased side effects.

For children: It hasn’t been established that donepezil is safe or effective for use in children under the age of 18 years.

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