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Desmopressin Side Effects

desmopressin side effects

Description

Desmopressin is used to control the amount of urine your kidneys make. Normally, the amount of urine you make is controlled by a certain substance in the body called vasopressin. In people who have "water diabetes" (diabetes insipidus) or certain kinds of head injury or brain surgery, the body does not make enough vasopressin. Desmopressin is a man-made form of vasopressin and is used to replace a low level of vasopressin. This medication helps to control increased thirst and too much urination due to these conditions, and helps prevent dehydration.

Desmopressin is also used to control nighttime bedwetting in children. It reduces how often your child urinates and decreases the number of bedwetting episodes.

How does this medication work? What will it do for me?

The tablet form of desmopressin belongs to the class of medications known as antidiuretics. It is a hormone taken by mouth to control excessive urination during the night (bedwetting). It is also used to treat central diabetes insipidus, a condition where the kidneys are unable to conserve water due to a lack of antidiuretic hormone (ADH). This condition causes frequent urination and thirst. Desmopressin is also used to treat temporary conditions of frequent thirst and urination after head trauma or surgery in the pituitary gland.

This medication works by acting on the kidneys to reduce the amount of urine they produce. It usually starts to work within an hour and lasts for 7 to 9 hours.

Side effects

  • flushing or redness of skin
  • headache
  • nasal congestion
  • runny nose
  • stomach cramps
  • upset stomach (nausea)
  • confusion
  • flushing
  • headache (continuing)
  • nausea
  • vomiting
  • weight gain

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug are: tolvaptan, "water pills"/diuretics (such as furosemide).

Precautions

Tell the doctor right away if you develop any illness that can cause water/mineral imbalance (including fever, diarrhea, vomiting, infections such as the flu) or if you experience conditions that require drinking more fluids (for example, exposure to very hot weather, strenuous exercise, persistent sweating). The doctor may need to stop or adjust desmopressin treatment, especially in children and older adults.

Children may be more sensitive to the side effects of this drug, especially water/mineral imbalance and a low level of sodium in the blood.

Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, older adults may be at greater risk for water/mineral imbalance and a low level of sodium in the blood while using this drug.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

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