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Darifenacin Xr

Darifenacin XR

What is Enablex?

Enablex (darifenacin) reduces muscle spasms of the bladder and urinary tract.

Enablex is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage).

Enablex may also be used for purposes not listed in this medication guide.

Enablex side effects

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

Get emergency medical help if you have any of these signs of an allergic reaction to Enablex: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using Enablex and call your doctor at once if you have:

  • severe stomach pain or constipation;
  • confusion, hallucinations
  • little or no urinating
  • pain or burning when you urinate
  • signs of dehydration--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin.

Common Enablex side effects may include:

  • nausea, indigestion
  • constipation
  • headache, dizziness
  • dry mouth
  • blurred vision.



Urinary retention

Uncontrolled narrow-angle glaucoma

Severe hepatic impairment

Paralytic ileus

GI or Gu obstruction



Bladder outflow obstruction, controlled narrow-angle glaucoma, decreased GI motility, renal/hepatic impairment

Angioedema of the face, lips, tongue, and/or larynx have been reported, in some cases angioedema occurred after the first dose

CNS anticholinergic effects reported including headache, confusion, hallucinations, and somnolence

Heat prostration may occur in the presence of increased environmental temperature

Use caution in patients with decreased GI motility, hiatal hernia, reflux esophagitis, and ulcerative colitis

Use caution in patients with controlled narrow-angle glaucoma and patients with hepatic impairment, or myesthenia gravis

Important information

You should not take Enablex if you are have untreated or uncontrolled narrow-angle glaucoma, a stomach disorder causing delayed emptying, or if you have trouble emptying your bladder.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Enablex can decrease perspiration and you may be more prone to heat stroke.

Stop using this medication and call your doctor if you have serious side effects such as hot and dry skin, extreme thirst, severe stomach pain or constipation, pain or burning when you urinate, or if you stop urinating.

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.


Protect from light

Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees F