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Dapoxetine Sildenafil

Dapoxetine Sildenafil

Description

Potential pharmacokinetic interactions between dapoxetine, a serotonin transporter inhibitor developed for the treatment of premature ejaculation (PE), and the phosphodiesterase-5 inhibitors tadalafil and sildenafil, agents used in the treatment of erectile dysfunction (ED), were investigated in an open-label, randomized, crossover study (n=24 men) comparing dapoxetine 60 mg, dapoxetine 60 mg+tadalafil 20 mg, and dapoxetine 60 mg+sildenafil 100 mg. Plasma concentrations of dapoxetine, tadalafil, and sildenafil were determined by liquid chromatography-tandem mass spectrometry. Tadalafil did not affect the pharmacokinetics of dapoxetine, whereas sildenafil increased the dapoxetine AUCinf by 22%; these effects were deemed not clinically important. Dapoxetine did not appear to affect the pharmacokinetics of tadalafil or sildenafil. Most adverse events were mild in nature. Thus, dapoxetine has no clinically important pharmacokinetic interactions with tadalafil or sildenafil, and the combinations are well tolerated.

How to take Sildenafil 100mg+Dapoxetine 60mg Tablets?

The Doctor’s suggestion is always advisable before starting to consume this pill. Sildenafil 100mg+Dapoxetine 60mg is an oral tablet should be consumed with a glass of water for dissolving easily. Overdoses are always restricted and do not need to take this pill on a daily basis. It should be taken once in a day (in an interval of 24 hours). Take this pill one hour prior to love making session. Because it takes time to show effects against sexual dysfunction & premature ejaculation.

Super P-Force Side Effects

  • Blood pressure increased
  • Dizziness
  • Headache
  • Somnolence
  • Tremor
  • Disturbance in attention
  • Paraesthesia
  • Vision blurred
  • Tinnitus
  • Sinus congestion
  • Yawning
  • Nausea
  • Diarrhoea
  • Abdominal pain
  • Dry mouth
  • Vomiting
  • Dyspepsia
  • Flatulence

How does it work?

Priligy tablets contain the active ingredient dapoxetine, which is a type of medicine known as a selective serotonin reuptake inhibitor. It is used to treat premature ejaculation in men.Dapoxetine works by increasing the activity of serotonin in the nervous system. Serotonin is a neurotransmitter that is involved in passing messages between nerve cells. It has various functions in the body and is involved in sending the nerve messages that result in ejaculation.

Dapoxetine 60mg Tablets Side Effects 

Some of the rare side effects of Sildenafil 100mg+Dapoxetine 60mg are headache, diarrhea, nausea and dizziness. Only few users suffer from these side effects. These side effects are common in those people who consume even other drugs with Sildenafil 100mg+Dapoxetine 60mg. Increasing the dosage randomly without consulting a physician also may be a cause of the side effects.

Overdosage

Symptoms of overdose with Dapoxetine HCl include serotonin-mediated adverse reactions such as somnolence, gastrointestinal disturbances such as nausea and vomiting, tachycardia, tremor, agitation and dizziness. In studies with healthy volunteers of single doses up to 800 mg Sildenafil Citrate, adverse reactions were similar to those seen at lower doses but incidence rates and severities were increased.

Warning

This medicine may make you feel sleepy or dizzy and so may reduce your ability to drive or operate hazardous machinery safely. Do not drive or operate machinery until you know how this medicine affects you and you are sure it won't affect your performance.

It is recommended that you avoid drinking alcohol when taking this medicine. Alcohol can increase the risk of side effects such as feeling dizzy and drowsiness, and may increase the risk of injury from fainting see below.

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