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Clindamycin &Tretinoin

Clindamycin &  Tretinoin

What is clindamycin and tretinoin topical?

Clindamycin is an antibiotic. It fights bacteria in the body.

Tretinoin is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly.

Clindamycin and tretinoin is a combination medicine used to treat severe nodular acne in adults and children who are at least 12 years old.

Clindamycin and tretinoin topical may also be used for purposes other than those listed in this medication guide.

Mechanism of Action

Veltin gel is a combination of 1.2% clindamycin, and 0.025% tretinoin. It combines the anti-inflammatory and antibiotic effects of clindamycin and tretinoin. Tretinoin prevents the formation of comedones by stimulating keratinocyte production and reducing their cohesiveness. The bacteriostatic effect of clindamycin prevents proliferation of the microbial flora, thereby stopping production of inflammatory mediators that result in pustular lesions.

How should I use clindamycin and tretinoin topical?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Using more medicine or applying it more often than prescribed will not make it work any faster, and may increase side effects.

Wash your hands before and after applying this medication.

Wash your face with a mild soap or cleanser and pat the skin dry with a clean towel.

Use only a pea-sized amount of clindamycin and tretinoin topical. Apply to your entire face every night at bedtime.

Do not wash your face more than 3 times daily while using this medication. Washing more often or scrubbing your face when you wash it can make your acne worse.

Avoid getting this medication in your eyes, mouth, or nose (or in the creases of your nose), or on your lips. If it does get into any of these areas, wash with water. Do not apply this medicine to sunburned, windburned, dry, chapped, irritated, or broken skin.

Clindamycin and tretinoin topical side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • severe redness, burning, stinging, or scaling of treated skin areas; or
  • diarrhea that is watery or bloody.

Common side effects may include:

  • mild skin irritation, dryness or peeling;
  • mild skin redness; or
  • itching of treated skin.

This is not a complete list of side effects and others may occur.

What is clindamycin and tretinoin topical?

Clindamycin is an antibiotic. It fights bacteria in the body.

Tretinoin is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly.

The combination of clindamycin and tretinoin is used to treat severe nodular acne in adults and children who are at least 12 years old.

Clindamycin and tretinoin topical may also be used for purposes other than those listed in this medication guide.

Clindamycin-Tretinoin Topical Interactions

Avoid washing treated skin or applying other skin products for at least 1 hour after applying this medicine.

Avoid using other medications on the areas you treat with clindamycin and tretinoin topical unless your doctor tells you to. Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop using this medicine and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

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