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Clindamycin And Nicotinamide

clindamycin and nicotinamide

Nicotinamide is mostly used as a dietary supplement. It is a type of vitamin that is used as medication. Nicotinamide can be taken orally. The medicine is also available in the form nicotinic acid to treat niacin deficiency diseases like pellagra. In the cream form, it is beneficial for the treatment of acne and other kinds of skin inflammation, as the medicine has anti-inflammatory properties. Nicotinamide is known to effectively decrease the sebum excretion. The medicine also comes in a gel form for easier application in hot, humid environments.

Nicotinamide has made it to the List of Essential Medicines of the World Health Organization, as one of safest and necessary medicines. Nicotinamide, if taken in small doses does not pose any potential threat to pregnant women. However, overdosing may cause some liver disorders.

The properties of this drug help to increase the effectiveness of radiation therapy, and enhances blood flow to the malignant tumours thereby reducing tumour hypoxia in patients receiving chemotherapy. It has a few other benefits when mixed with other nutritional compounds, such as relief from the pain of arthritis, adequate reduction of high cholesterol levels in the blood or prevention of Type 1 diabetes if the risks are detected early.

How is this medicine (Clindamycin Gel and Lotion) best taken?

Use clindamycin gel and lotion as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Follow how to use as you have been told by the doctor or read the package insert.
  • To gain the most benefit, do not miss doses.
  • Use as you have been told, even if your signs get better.
  • Wash your hands before and after use.
  • Do not take clindamycin gel and lotion by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
  • Clean affected part before use. Make sure to dry well.
  • Put a thin layer on the affected skin.
  • Shake lotion well before use.

Side effects and warnings

"Clindamycin can cause some stomach distress, as most antibiotics do," said Sternfeld. Other less serious side effects include:

  • joint pain
  • pain when swallowing
  • heartburn
  • white patches in the mouth
  • head or backaches

Other, more serious side effects should be treated by a doctor immediately, including:

  • blisters
  • rash
  • hives
  • difficulty breathing or swallowing
  • yellowing of the skin or eyes
  • decreased urination
  • fever, chills, and other flu-like symptoms
  • sores on mouth or throat
  • easy bruising or red or purple pinpoint spots under the skin
  • unusual bleeding (of the nose, mouth, vagina, or rectum)
  • facial swelling

There are no known reactions between alcohol or certain foods and clindamycin, so the normal diet can be continued unless a doctor says otherwise.

Women who are pregnant or planning to become pregnant should consult a doctor before taking clindamycin.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.