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Cisplatin Sigma

Cisplatin Sigma

Description

This product was recently added by customer request, and is available for your convenience. We strive to provide our customers with a one-stop shop for the entire scientific supplies category. More relevant content may be added as customer demand increases.

How it Work?

Cancerous tumors are characterized by cell division, which is no longer controlled as it is in normal tissue. "Normal" cell stop dividing when they come into contact with like cells, a mechanism known as contact inhibition. Cancerous cells lose this ability. Cancer cells no longer have the normal checks and balances in place that control and limit cell division. The process of cell division, whether normal or cancerous cells, is through the cell cycle. The cell cycle goes from the resting phase, through active growing phases, and then to mitosis (division).The ability of chemotherapy to kill cancer cells depends on its ability to halt cell division. Usually, the drugs work by damaging the RNA or DNA that tells the cell how to copy itself in division. If the cells are unable to divide, they die. The faster the cells are dividing, the more likely it is that chemotherapy will kill the cells, causing the tumor to shrink. They also induce cell suicide (self-death or apoptosis).

Uses

Treatment of advanced bladder cancer, metastatic ovarian cancer, and metastatic testicular cancer. Testicular, ovarian, bladder, head and neck, esophageal, small and non-small cell lung, breast, cervical, stomach and prostate cancers. Also to treat Hodgkin's and non-Hodgkin's lymphomas, neuroblastoma, sarcomas, multiple myeloma, melanoma, and mesothelioma.

When To Contact Your Doctor or Health Care Provider:

  • Contact your health care provide immediately, day or night, if you should experience any of the following symptoms:
  • Fever of 100.4°F (38°C) or higher or chills (possible signs of infection)
  • The following symptoms require medical attention, but are not an emergency. Contact your health care provider within 24 hours of noticing any of the following:
  • Nausea (interferes with ability to eat and unrelieved with prescribed medication)
  • Vomiting (vomiting more than 4-5 times in a 24 hour period)
  • Diarrhea (4-6 episodes in a 24 hour period)
  • No urine output in a 12 hour period
  • Blood in the urine
  • Pain or burning with urination

Precaution

  • Before starting cisplatin treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, products containing aspirin unless your doctor specifically permits this.
  • Cisplatin may be inadvisable if you have a history of severe allergic reaction to cisplatin, carboplatin, other platinum-containing formulations or mannitol.
  • Do not receive any kind of immunization or vaccination without your doctor's approval while taking cisplatin.

Side Effect

  • Peripheral neuropathy: Although less common, a serious side effect of decreased sensation and paresthesia (numbness and tingling of the extremities) may be noted. Sensory loss, numbness and tingling, and difficulty in walking may last for at least as long as therapy is continued. These side effects may become progressively more severe with continued treatment, and your doctor may decide to decrease your dose. Neurologic effects may be irreversible.
  • Loss of appetite
  • Taste changes, metallic taste
  • Increases in blood tests measuring liver function. These return to normal once treatment is discontinued. (see liver problems).
  • Hair loss may cause hair loss; however, this side effect is uncommon.

Know More About This Medicine and Buy Now : MedyPharma.com

 

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