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Cisplatin

Cisplatin

Description

Cisplatin is used to treat non-small cell lung cancer, bladder cancer, cervical cancer, ovarian cancer, head and neck cancer, and testicular cancer.Cisplatin is a type of chemotherapy drug. Specifically, it is part of a class of drugs known as platinum-containing compounds, which belong in the larger group of alkylating agents. Cisplatin works by interfering with the process of cell division, destroying cancer cells and slowing or stopping the spread of cancer.This medication is given as an injection into a vein (intravenous). Each injection takes about one hour, though it sometimes is administered over a longer period, from 6 to 8 hours. It is usually given once every three to four weeks. The exact dose and schedule of cisplatin plus depends on your size and how well your kidneys are working, among other factors. Your doctor will recommend a regimen tailored to your needs.

How cisplatin is given

You usually have cisplatin in the chemotherapy day unit or during a stay in hospital. A chemotherapy nurse will give it to you. It may be given with other chemotherapy drugs or with radiotherapy. During treatment, you usually see a cancer doctor, a chemotherapy nurse or a specialist nurse. This is who we mean when we mention doctor or nurse in this information.

How it works

This chemotherapy drug destroys quickly dividing cells, such as cancer cells.Before or on the day of treatment, a nurse or person trained to take blood (phlebotomist) will take a blood sample from you. This is to check that it is okay for you to have chemotherapy.

Side Effect

To prevent problematic interactions between cisplatin and other drugs, be sure to tell your doctor if you are allergic to any medications. Also inform your doctor of any medications, both prescription and nonprescription, and supplements you are taking. You should also inform your doctor if you have or ever had diabetes, high blood pressure, liver tumor, liver disease or kidney disease, if you are pregnant or planning to become pregnant, or if you are breastfeeding.

Possible side effects of cisplatin may include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Hair loss
  • Loss in ability to taste food
  • Hiccups
  • Dry mouth, dark urine, decreased sweating, dry skin, or other signs of dehydration

Warning

Cisplatin injection (cisplatin injection (cisplatin (cisplatin injection) injection) ) should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents. Appropriate management of therapy and complications is possible only when adequate diagnostic and treatment facilities are readily available.Cumulative renal toxicity associated with cisplatin (cisplatin injection) is severe. Other major dose-related toxicities are myelo-suppression, nausea, and vomiting.Ototoxicity, which may be more pronounced in children, and is manifested by tinnitus, and/or loss of high frequency hearing and occasionally deafness, is significant.

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