Tenvir L

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  • Manufacturer : Cipla Ltd
  • Equivalent Brands : Cimduo
  • Generic Brands : Lamivudine / Tenofovir

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Pack Size Price Qty Price Per Unit Addtocart
30 Tablet/s $54.00 $1.80
60 Tablet/s $102.00 $1.70
90 Tablet/s $148.00 $1.64
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1. Buy Tenvir L Tablet Online

Tenvir L Tablet is a nucleoside analogue. It is used in combination with other medications to treat HIV infection. It functions by interfering with the growth of the HIV infection.

On using this medication you may experience side effects such as nausea, joint pain, difficulty sleeping, diarrhea, cough, dizziness, swelling of the mouth, headache, reduced appetite, weakness, vomiting, darkening of the urine, numbness, mental/ mood disorders, ear pain, itchiness, sore throat and chest pain. If your reactions persist or worsen over time seek the help of your health care provider right away.

Before using this medication tell your doctor if; you are allergic to any ingredient contained within Tenvir L Tablet, you are taking any other medications especially emtricitabine and zalcitabine, you have enlarged liver/ high levels of lactic acid/ abnormal liver functioning/ muscle problems/ kidney problems/ lactic acidosis/ nerve disorder/ pancreas problem, you are overweight, you are pregnant or are planning to become pregnant or are nursing a baby.

The dosage for this medication should be based on your medical history and current condition. The usual dose in adults for HIV infection is about 150 mg twice daily or 300 mg once daily.

2. How To Tenvir L Work?

Tenvir L Tablet is a combination of two anti-HIV medicines: Lamivudine and Tenofovir. They prevent HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

3. Drug interaction of Tenvir L

Taking nephrotoxic drug therapies with Tenvir-L can heighten risks of renal impairment. Drugs associated with peripheral neuropathy or pancreatitis including alcohol, sulfonamides, zalcitabine, stavudine, dapsone, isoniazid, and IV pentamidine should be taken with extreme precaution or avoided. Tenvir-L may heighten the risks of didanosine associated side effects. Lopinavir/ritonavir and atazanavir may worsen side effects associated with Tenvir-L. Tenvir-L should be discontinued if this occurs. Atazanavir without ritonavir must not be administered with Tenvir-L

4. Side Effects of Tenvir L

In addition to its intended effect, Tenvir L Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

  • diarrhea
  • nausea
  • asthenia
  • vomiting
  • peripheral neuropathy
  • dyspepsia
  • dizziness
  • headache
  • fatigue
  • insomnia
  • anorexia
  • abdominal cramps
  • myalgia
  • arthralgia
  • depressive disorders
  • renal impairment or failure
  • tubular necrosis
  • hepatotoxicity
  • fanconi syndrome
  • lactic acidosis
  • pancreatitis
  • proximal tubulopathy
  • hypophosphatemia

5. Warning of Tenvir L tablet

Anyone with a creatinine clearance less than 50 ml/min must not take Tenvir-L. Worsening of hepatic symptoms have been documented in patients with hepatitis B after they stopped taking Tenvir-L. For patients with hepatitis C, co-administering interferon alfa and ribavirin with Tenvir-L can heighten risks for hepatic decompensation. Use of didanosine is not recommended when beginning Tenvir-L because it can hinder Tenvir-L's effectiveness.

6. Precaution of Tenvir L tablet

Coadministration of tenofovir DF and didanosine should be undertaken with caution and patients receiving this combination should be monitored closely for didanosine associated adverse reactions. Didanosine should be discontinued in patients who develop didanosine-associated adverse reactions.

When administered with tenofovir DF, Cmax and AUC of didanosine  increased significantly. The mechanism of this interaction is unknown. Higher didanosine concentrations could potentiate didanosine-associated adverse reactions, including pancreatitis and neuropathy. Suppression of CD4+ cell counts has been observed in patients receiving tenofovir DF with didanosine 400 mg daily.

In patients weighing greater than 60kg, the didanosine dose should be reduced to 250 mg when it is coadministered with tenofovir. In patients weighing less than 60 kg, the didanosine dose should be reduced to 200 mg once daily when it is coadministered with tenofovir DF. When coadministered, tenofovir and didanosine EC may be taken under fasted conditions or with a light meal (<400 kcal, 20% fat). For additional information on coadministration of tenofovir DF and didanosine, please refer to the full prescribing information for didanosine.

In patients receiving tenofovir DF concomitantly with sofosbuvir/velpatasvir, monitor for adverse reactions associated with tenofovir DF.

In patients receiving tenofovir DF concomitantly with ledipasvir/sofosbuvir without an HIV-1 protease inhibitor/ritonavir or an HIV-1 protease inhibitor/cobicistat combination, monitor for adverse reactions associated with tenofovir DF.

In patients receiving tenofovir DF concomitantly with ledipasvir/sofosbuvir and an HIV-1 protease inhibitor/ritonavir or an HIV-1 protease inhibitor/cobicistat combination, consider an alternative HCV or antiretroviral therapy, as the safety of increased tenofovir concentrations in this setting has not been established. If coadministration is necessary, monitor for adverse reactions associated with tenofovir DF.

7. Uses of Tenvir L

Tenvir L Tablet is used in the treatment of HIV infection.

8. Storage of Tenvir L

Store in a cool, dry place.

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