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Can Ranitidine Cause Positive Drug Test

Can Ranitidine Cause Positive Drug Test

What is a false positive drug test?

A worry for anyone undergoing drug testing - whether it be a urine, hair, saliva or blood test - is the possibility of a false positive result. ... In some rare cases, a drug test may report the presence of illicit or prescription drugs in the immunoassay, although the person has not used these drugs.

Why Can Zantac Cause False Positives For Methamphetamine?

The most common type of drug test used is a simple, urine based immunoassay test. Immunoassay tests include the EIA (Enzyme Linked Immunoassay) test and the CEDIA (Closed Enzyme Donor Immunoassay) test, which use similar principles.

Uses

Ranitidine is useful in any situation where stomach irritation is an issue and ulceration is a concern. It is often used in the treatment of Helicobacter infection, inflammatory bowel disease, canine parvovirus, kidney failure, ingestion of a toxin that could be ulcerating (an over dose of aspirin, for example), any disease involving protracted vomiting, or used chronically in combination with medications that may have stomach irritating properties.Immunoassay tests work by utilizing antibodies to react to specific drug compounds. When a specified drug is present in a test urine sample, an antibody binds to it, which produces a reaction and is recorded as a "positive" test.

Dosages

Adults: 150 mg P.O. b.i.d. or 300 mg h.s. Doses up to 6 g daily may be given to patients with Zollinger-Ellison syndrome. For parenteral use, 50 mg I.V. or I.M. q 6 to 8 hours.

Children ages 1 month to 16 years: For treatment of duodenal and gastric ulcers, 2 to 4 mg/kg P.O. b.i.d. Maximum, 300 mg daily.

Overdose

No cases of overdose have been reported. However, treatment would involve emesis or gastric lavage and supportive measures as needed. Drug is removed by hemodialysis.

Precaution

The dose of ranitidine may require reduction in patients with liver or kidney disease as these diseases tend to prolong drug activities.

  • It appears that ranitidine is safe for use in pregnancy but should probably be avoided during lactation.
  • The use of ranitidine can cause a urine dipstick to falsely test positive for protein.

Side Effects

The H2 blockers as a group have a limited potential for side effects, hence their recent release to over the counter status.There have been some reports of exacerbating heart rhythm problems in patients who already have heart rhythm problems so it may be prudent to choose another means of stomach acid control in heart patients.

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