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Buytenofovir Gel Online

Buytenofovir Gel Online

Tenofovir Gel Provides Protection Against Herpes  

Tenofovir, the antiretroviral, when used as a vaginal gel, has been proven to protect women against the herpes simplex virus. A study published in the Cell Host and Microbe journal reveals that due to higher concentrations reaching the vaginal cells in the gel form of the drug as opposed to the oral formulation, the drug’s use can extend to reducing the risk of contracting the herpes virus (HSV). The study was carried out by the Catholic University of Leaven, the University of Rome, the National Institute of Child Health and Human Development and Gilead Sciences.

The gel form of the drug stops the spread of the herpes virus by disabling its DNA enzyme and reduces the risk of contracting herpes simplex infections as well as HIV infections. It has always been known to inhibit the reproduction of the HIV virus but this study highlights its potential regarding HSV. HSV in its shedding phase is contractible even when infected partners present as asymptomatic.

HIV and herpes are closely associated and those who have the herpes virus and who are exposed to the herpes virus are more likely to contract HIV than those who do not carry the herpes virus.

Tenofovir is converted by human tissue into a form that inhibits the activity of the HIV virus and now we know that it does the same for herpes simplex. The study examined HSV infected group cells and individual cells and it was proven that the drug in high concentrations stopped the reproduction of the virus. Furthermore, mice treated with tenofovir and which were infected with herpes experienced no symptoms of herpes and lived longer.

Taking the drug orally will not affect the HSV virus but there is approximately 100 times the amount of the drug present in the gel form when administered directly to the vaginal tissues. Safety and efficacy studies will need to be carried out before the drug is sold in this form and for this use but this could be a breakthrough preventative treatment for a virus that stays with an infected individual for life.

Tenofovir Gel Lowered Risk for HIV and HSV-2 Infections

The trial showed that women using a gel containing tenofovir before and after sexual intercourse had a 39% lower risk of being infected with HIV compared with women using a placebo. During the course of the trial, 38 women in the tenofovir group and 60 women in the placebo group became HIV-positive. The incidence of HIV infection in the tenofovir group was 5.6 per 100 women-years vs 9.1 per 100 women-years in the placebo group, giving an incidence rate ratio of .61 (95% confidence interval,.4 - .94; P = .017).

Common use

Protonix accumulates in the tubules of parietal cells of the stomach and transforms into its active form that  interacts with the H+-K+-ATP-ase. Protonix inhibits this enzyme and prevents transfer of hydrogen ions from the parietal cells into the stomach cavity this way blocking the final stage of hydrochloric acid secretion. Protonix inhibits basal and stimulated (regardless type of a stimuli - acetylcholine, histamine, gastrin) secretion of hydrochloric acid. This medication is used to treat acute stage of duodenal or gastric ulcers, including those caused by treatment with anti-inflammatory non-steroid medications, gastroesophageal reflux disease (moderate and severe); Zollinger-Ellison syndrome, eradication of H. pylori in patients with a peptic ulcer to reduce the frequency of relapses.

Dosage and directions

Take exactly as administered by your doctor. Usually for patients with stomach or duodenum ulcers, gastroesophageal reflux disease Protonix is recommended as 40 mg daily dose. Treatment continues mostly during four weeks. Combined treatment with antibiotics (amoxicillin and clarithromycin) directed eradicate H. pylori in patients with ulcers in stomach and duodenum requires Protonix 40 mg daily divided in two doses: take one tablet before breakfast and before supper, do not chew or crash it, eat it whole with a glass of water. In case you purchased Protonix oral granules take them mixed only with applesauce or apple juice to make swallowing easy. Do not use any other type of liquid or soft food for it. Do not crush, chew, or break a delayed-release tablet.

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