1. Buy Triomune 40mg Online
Triomune 150 Mg/40 Mg/200 Mg Tablet is a nucleoside analogue. It is used in combination with other medications to treat HIV infection. It functions by interfering with the growth of the HIV infection.
On using this medication you may experience side effects such as nausea, joint pain, difficulty sleeping, diarrhea, cough, dizziness, swelling of the mouth, headache, reduced appetite, weakness, vomiting, darkening of the urine, numbness, mental/ mood disorders, ear pain, itchiness, sore throat and chest pain. If your reactions persist or worsen over time seek the help of your health care provider right away.
Before using this medication tell your doctor if; you are allergic to any ingredient contained within Triomune 150 Mg/40 Mg/200 Mg Tablet, you are taking any other medications especially emtricitabine and zalcitabine, you have enlarged liver/ high levels of lactic acid/ abnormal liver functioning/ muscle problems/ kidney problems/ lactic acidosis/ nerve disorder/ pancreas problem, you are overweight, you are pregnant or are planning to become pregnant or are nursing a baby.
2. How To Triomune 40mg Work?
Triomune tablets contain a combination of 3 antiretroviral drugs stavudine, lamivudine and nevirapine, which are effective only against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). These three drugs each work by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT) which is needed for the virus to be able to replicate.
Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. Nevirapine in Triomune tablets is a dipyridodiazepine derivative non-nucleoside reverse transcriptase inhibitor (NNRTI); nucleosides are the precursors to the building blocks of DNA and RNA.
Nevirapine in Triomune tablets acts by binding to a specific site on the RT enzyme, the enzyme's active site known as the NNRTI pocket, disrupting the catalytic site of the enzyme, and blocking its action in a manner that is noncompetitive with nucleosides.
Stavudine and lamivudine are both nucleoside analogue reverse transcriptase inhibitors (NRTI), which means that they block the action of RT by competing with one of the nucleosides needed to transcribe the viral RNA into DNA, becoming incorporated into the chain of newly synthesized viral DNA and preventing it from growing (chain termination).
Stavudine is an analogue of thymidine and lamivudine is an analogue of cytidine. The combined action of the three antiiretroviral drugs in Triomune tablets prevents the integration of the virus into the DNA of the infected CD4+ immune cell by 2 different mechanisms, which inhibits the replication of HIV so that no more virus can be produced and this reduces the viral load (amount of virus).
Triomune 40 slows down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.
3. What is Triomune 40mg Tablet?
Triomune is a fixed dose combination treatment for Human Immunodeficiency Virus (HIV) infection in adults. Triomune tablets are used to treat HIV patients who have already been treated with other HIV medications and have responded well to each of the drugs in the combination; and are also able to tolerate each of these medications, at the recommended doses without requiring a dose adjustment due to low weight.
HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection, which can lead to opportunistic life-threatening infection (infections that would not normally be harmful); also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS).
Triomune tablets prevent or slow down the ability of HIV to replicate and spread, which keeps the amount of virus (viral load) down to a low level; allowing the numbers of CD4+ cells to increase, so that the immune system can recover, reducing the risk of disease progression.
Triple drug therapy with Triomune 40 makes it easier to take the medications regularly, which helps improve compliance and helps prevent resistance of HIV to individual drugs.
4. How To Take Triomune 40mg Tablet?
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Triomune 150mg/40mg/200mg Tablet is to be taken empty stomach.
Take it preferably 1 hour before food.
5. Side Effects of Triomune 40mg
- Insomnia (difficulty in sleeping),
- Dryness in mouth,
- Peripheral neuropathy (tingling and numbness of feet and hand).
6. Warning of Triomune 40mg tablet
Discontinue use If there is rapid increase in aminotransferase Levels, Progressive Hepatomegaly, or Metabolic or Lactic Acidosis of unknown origin. Discontinue use If Clinical Signs, symptoms or Lab abnormalities suggestive of Pancreatitis develop. Hepatomegaly or other risk factors For Hepatic Impairment. Monitor hepatic function In chronic hepatitis B Patients. exclude HIV Infection Prior To Hepatitis B Therapy. Renal Impairment. Pregnancy.
7. Precaution of Triomune 40mg tablet
You should not use Triomune tablets if you:
- are allergic to stavudine, lamivudine or nevirapine or any ingredients in Triomune
- are pregnant or are breastfeeding
- have kidney or liver disease
- are just starting HIV therapy and have not used nevirapine previously
- have previously experienced peripheral neuropathy (damage to nerves in hands and feet causing tingling, numbness and pain)
- are taking medicines that interact with Triomune, including, the anticancer drugs doxorubicin and ribavirin, the antibiotics trimethoprim/sulfamethoxazole, rifampin for tuberculosis, other antiretrovirals like efavirenz, indinavir, lopinavir, nelfinavir and saquinavir, the antifungal ketoconazole, oral contraceptives, methadone
8. Uses of Triomune 40mg
Triomune 150mg/40mg/200mg Tablet is used in the treatment of HIV infection.
Triomune 40 Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
- Hiv-1 infection
- Hiv infection
- Hepatitis b virus infection
- Suppression of immunity
9. Storage of Triomune 40mg
You should store your Triomune below 25°C in a cool dry place.