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  • Manufacturer : Bayer Pharmaceuticals Pvt Ltd
  • Equivalent Brands : Stivarga
  • Generic Brands : Regorafenib

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Pack Size Price Qty Price Per Unit Addtocart
28 Tablet/s $790.00 $28.21
56 Tablet/s $1.57 $0.03
84 Tablet/s $2.35 $0.03
Nublexa 40 Mg is available to buy in increments of 1

1. Buy Nublexa 40mg Online

Nublexa (Regorafenib) 40mg is  a prescription drug used in the treatment of colorectal cancer. It blocks the action of abnormal  protein that causes cancer and thereby This helps to stop or slow the spread of cancer cells. It is also used to treat certain type of stomach, bowel, or esophagus cancer called gastrointestinal stromal tumors (GIST).

Regorafenib works by blocking particular proteins on cancer cells that encourage the cancer to grow. These proteins are called protein kinases. Regorafenib is called a protein tyrosine kinase inhibitor (TKI) or cancer growth blocker. Regorafenib stops a number of different proteins being made and is called a multi kinase inhibitor. It works by stopping signals that tell cancer cells to grow. It also stops the cancer cells growing blood vessels that they need. Blocking blood vessel growth is called anti angiogenesis treatment.

2. How To Nublexa 40mg Work?

Regorafenib is in a class of medications called kinase inhibitors. It works by blocking some proteins on certain cancer cells that tell the cancer to grow. In this way, this cancer medicine may stop cancer from growing for a period of time. Nublexa may also stop the creation of new blood vessels that feed cancer cells.

3. What is Nublexa 40mg Tablet?

Nublexa belongs to the group of medications called antineoplastics, or anti-cancer medications. It is prescription medicine that contains Regorafenib 40mg as an active ingredient. Nublexa comes in tablet form and its each pack contains 28 tablets. This medicine should only be taken under the supervision of a health care professional. Follow the descriptions given you by your doctor regarding the right medicine, at the right time, and at the right dosage.

Nublexa (Regorafenib) is used in the treatment of metastatic colorectal cancer (cancer of colon and rectum). It is also used to treat a rare type of tumor that can affect the esophagus, stomach, or intestines (gastrointestinal stromal tumor).

4. Side Effects of Nublexa 40mg

  • Rash
  • Weakness
  • Reduced blood platelets
  • Difficulty in speaking
  • Haemorrhage
  • Vomiting
  • Pain
  • Nausea
  • Infection
  • Hair loss
  • Fever
  • Anemia
  • Diarrhoea
  • Increased blood pressure
  • Decreased appetite
  • Mucosal inflammation
  • Stomatitis (Inflammation of the mouth)

5. Warning of Nublexa 40mg tablet

Abnormalities of liver function tests (alanine aminotransferase [ALT], aspartate aminotransferase [AST] and bilirubin) have been frequently observed in patients treated with Stivarga. Severe liver function test abnormalities (Grade 3 to 4) and hepatic dysfunction with clinical manifestations (including fatal outcomes) have been reported in a small proportion of patients. In clinical trials, a higher incidence of severe liver function test abnormalities and hepatic dysfunction was observed in Asian (in particular Japanese) patients treated with Stivarga as compared with Caucasians.

It is recommended to perform liver function tests (ALT, AST and bilirubin) before initiation of treatment with Stivarga and monitor closely (at least every two weeks) during the first 2 months of treatment. Thereafter, periodic monitoring should be continued at least monthly and as clinically indicated.

6. Precaution of Nublexa 40mg tablet

Do not repeat dose after vomiting. Seek your doctor’s advice. In case of missed dose, take the dose as soon as you remember on the same day. Do not take a missed dose next day. 

Seek immediate medical attention if you experience severe chest pain which may spread from the chest to shoulders, arms, back, neck, teeth, jaw or stomach, sudden colds sweats, or fainting.

Inform your doctor if you have any liver disorders, bleeding disorders, high blood pressure, underwent surgery in the past or have a planned surgery.

Inform your doctor, if you experience vomiting, stomach pain, bowel complaints with dark stools, pain, redness or blisters on palms or soles, or non-healing wounds, severe headache, eye disturbance, fits, confusion, memory loss or any other altered mental symptoms. 

Do not drive or operate machinery, if you experience treatment-related symptoms which could affect your ability to concentrate and react. 

Men and women planning pregnancy should use effective birth control while they are taking regorafenib for 2 months after they stop taking it.

Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.

Do not take if patient is allergic to regorafenib or any of its ingredients.

7. Uses of Nublexa 40mg

Nublexa 40mg Tablet is used in the treatment of cancer of colon and rectum.

Regorafenib is a treatment for bowel cancer that has spread to other parts of the body – when other treatments are no longer working or are unsuitable and gastro intestinal stromal cancer (GIST) – a rare type of soft tissue sarcoma of the stomach or intestines. This treatment is used when other treatments are no longer working or are unsuitable

8. Storage of Nublexa 40mg

Store Regorafenib at 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).

Consider storing your medications separately from your other family members. This will make it less likely that you take the wrong ones by mistake.

Make sure to always keep your medicine in an area of your home that is out of the reach of children and pets.

Store Nublexa in the original package in order to protect from moisture.

Keep this medicine away from heat, light and humidity. Improper storage can affect the effectiveness and shelf life of your medicine.

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