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Botilinum Toxin Type- A

Botilinum Toxin Type- A

Description

Formerly known as botulinum toxin type A; IM toxin that reduces local muscle activity.

Approved and off-label uses include cervical dystonia, blepharospasm, strabismus, upper limb spasticity, lower limb spasticity, facial wrinkles, migraine prophylaxis, cerebral palsy, low back pain, excessive sweating, overactive bladder, and urinary incontinence associated with neurologic conditions.

Distant spread of botulinum toxic effects from the site of injection has resulted in symptoms suggestive of systemic botulism (including respiratory compromise and death) after the use of botulinum toxins types A and B.

Botulinum toxins types differ and different types are not exchangeable or substitutable for one another.

Interactions

Myobloc may impair your vision or depth perception. Be careful if you drive or do anything that requires you to be able to see clearly.

Other drugs such as cold or allergy medicines, muscle relaxers, sleeping pills, bronchodilators, bladder or urinary medications, and irritable bowel medications can increase some of the side effects of Myobloc. Tell your doctor if you regularly use any of these medicines.

Tell your doctor about all your current medicines and any you start or stop using, especially:

This list is not complete. Other drugs may interact with Myobloc, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Dosage

This medicine is injected into a muscle. A doctor, nurse, or other healthcare provider will give you this injection. Myobloc injections should be spaced at least 3 months apart.

Your injection may be given into more than one area at a time, depending on the condition being treated.

The effects of a Myobloc injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin.

Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection.

Warnings

Effects of all botulinum toxin products may spread from the area of injection to produce symptoms consistent with botulinum toxin effects

These symptoms may include asthenia, generalized muscle weakness, diplopia, blurred vision, ptosis, dysphagia, dysphonia, dysarthria, urinary incontinence, and breathing difficulties

These symptoms have been reported hours to weeks after injection

Swallowing and breathing difficulties can be life threatening, and death have been reported

The risk of symptoms is probably greatest in children treated for spasticity, but symptoms can also occur in adults treated for spasticity and other conditions, particularly in those patients who have underlying conditions that would predispose them to these symptoms

Storage

Store at room temperature between 68°F and 77°F (20°C and 25°C).

Don’t store this medication in moist or damp areas, such as bathrooms.

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