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Azithromycin For Bronchitis

azithromycin for bronchitis

Azithromycin for Acute Bronchitis?

An important criterion for performing meta-analysis is whether the studies are measuring the same underlying magnitude of effect.2 When there is statistical evidence of lack of homogeneity, calculating a pooled estimate of size effect is of dubious validity.3 There seems to be a clear indication that one outlier study does not belong to the same group of studies. The authors of the meta-analysis were aware that one trial was an outlier and that the results are heterogeneous (p. 693). Despite this, they ignored the heterogeneity and based their conclusions on the questionable common effect estimate.

Acute exacerbation of chronic bronchitis is a serious medical condition. Azithromycin seems to have a clear efficacy advantage compared with other antibiotics in treating this condition. Treatment with azithromycin is c. 50% more effective than treatment with the comparator antibiotics. That is a major clinical advantage that should translate into appropriate clinical recommendations and improved patient outcomes.


It is always important to share with your doctor and pharmacist all of the medications you are taking.

This includes not only all of your prescription medicine, but also products that may not seem like medication, such as over-the-counter drugs, vitamins and other dietary supplements (nutritional shakes, protein powders, etc.), and herbals along with any legal or illegal recreational drugs.

You should not take Azithromycin if you are taking

  • Pimozide (Orap)
  • BCG live (Theracrys)
  • Dronedarone


Azithromycin is taken as a pill or liquid. It's also given as intravenous (IV) injection in hospitals. Packets of powder are mixed with water to create the liquid solution.

Azithromycin may be taken with or without food.

Doctors sometimes prescribe azithromycin for shorter periods than they do for other antibiotics, such as in a one-day "mega-dose," or for three or five days, using the Z-Pak, which starts at a higher dose than longer regimens.

Side Effects

Get emergency medical help right away if you experience any of the following:

  • Chest pain
  • Seizures
  • Swelling of the feet or ankles
  • Inflammation of the colon (symptoms may include abdominal pain, severe diarrhea, fatigue)
  • Fluid build-up between the lungs and the chest wall (symptoms may include chest pain or heaviness, or difficulty breathing difficulties)
  • Low count of white blood cells (this is usually discovered in blood tests, but if you have symptoms, they may include weakness, tiredness, shortness of breath, or infections that do not go away)


Azithromycin can cause abnormal changes in the electrical activity of the heart, which may lead to deadly irregular heart rhythm, according to a special warning by the FDA in 2012.

If you have a heart-rhythm condition, such as a slow or irregular heartbeat, or take drugs to treat these conditions, you should talk to your doctor about it before taking azithromycin.

Your doctor also should make sure you have normal blood levels of potassium and magnesium before prescribing azithromycin.

In addition, you should not take azithromycin if you:

  • Are allergic to azithromycin or any of its inactive ingredients
  • Have a form of jaundice known as cholestatic jaundice, in which bile backs up into the liver and causes a yellowing of the skin, eyes, or nails

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