My Cart

0 Item(s): $0.00

You have no items in your shopping cart.

Azelastine/Fluticasone Propionate

Azelastine/Fluticasone Propionate


Azelastine and fluticasone combination nasal spray is used to treat an itchy or runny nose, sneezing, or other symptoms caused by seasonal hay fever (allergic rhinitis).

Azelastine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes.

Fluticasone is a steroid (cortisone-like medicine). It works by preventing the inflammation that occurs with allergic reactions.

This medicine is available only with your doctor's prescription.

What this medicine is used for

The name of your medicine is APO-AZELASTINE/FLUTICASONE 125/50 Nasal Spray. It contains the active ingredients azelastine hydrochloride and fluticasone propionate.

It is used to treat:

  • Allergic rhinitis (hayfever and other allergies.
  • Rhinoconjunctivitis (allergy-induced symptoms in the nose and eyes.

In adults and children 12 years and older where use of a combination (intranasal antihistamine and glucocorticoid) is appropriate.

Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed this medicine for another reason.

This medicine is available only with a doctor's prescription.

How it works

This medicine contains two active ingredients: azelastine hydrochloride and fluticasone propionate.

Azelastine hydrochloride belongs to a group of medicines called antihistamines. Antihistamines work by preventing the effects of substances such as histamine that the body produces as part of an allergic reaction. This reduces symptoms of an allergic rhinitis.

Fluticasone propionate belongs to a group of medicines called corticosteroids which are used to help reduce inflammation.

Due to the fast relief and the anti-inflammatory effect, Azelastine/Fluticasone 125/50 Nasal Spray is more effective on symptoms relating to the nose and eyes than either antihistamine or corticosteroid therapy alone.

There is no evidence that this medicine is addictive.

What are some other side effects of Azelastine and Fluticasone?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Headache.
  • Nosebleed.
  • Nose irritation.
  • Change in taste.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.


Avoid use in recent nasal ulcers, nasal surgery, or nasal trauma. Respiratory tract tuberculosis. Infections (eg, fungal, bacterial, viral, ocular herpes simplex). Avoid exposure to chickenpox and measles; if exposed, consider anti-infective prophylactic therapy. If adrenal insufficiency exists following systemic corticosteroid therapy, replacement with topical corticosteroids may exacerbate symptoms of adrenal insufficiency (eg, lassitude, depression). Monitor growth routinely in children. Monitor for hypercorticism and HPA axis suppression (if occur discontinue gradually), and Candida infection or other nasal mucosal changes. History of increased intraocular pressure, glaucoma, and/or cataracts; monitor any change in vision. Avoid eyes. Pregnancy. Nursing mothers: monitor infants.