My Cart

0 Item(s): $0.00

You have no items in your shopping cart.

Azelastine Hcl

Azelastine Hcl

What is azelastine?

Azelastine nasal spray is a prescription drug. It’s available as the brand-name drugs Astepro and Astelin. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, the brand-name drug and the generic version may be available in different forms and strengths.

Azelastine nasal spray may be used as part of a combination therapy. This means you may need to take it with other medications.

Why it’s used

Azelastine nasal spray is used to provide relief from allergy symptoms. These can include sneezing and runny nose.

How it works

Azelastine belongs to a class of drugs called antihistamines. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Azelastine works by inhibiting the release of a chemical called histamine from the cells in your body. This helps relieve allergic symptoms such as sneezing or runny nose.

Azelastine side effects

Azelastine nasal spray may cause drowsiness. It may also cause other side effects.

More common side effects

The more common side effects of azelastine nasal spray can include:

  • fever
  • bitter taste in your mouth
  • nose pain or discomfort
  • nosebleeds
  • headache
  • sneezing
  • drowsiness
  • upper respiratory tract infection
  • cough
  • vomiting
  • ear infection
  • skin rash
  • sore throat

These effects may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.


Check the label on the medicine for directions about your specific dose.

Wash your hands thoroughly before applying medicine to your eyes. Tilt your head back and gently pull your lower eyelid down to form a pouch. Hold the dropper directly above your eye, look up, and squeeze a drop of the medicine into the pouch. Close your eyes for a minute or two and with a fingertip gently press on the inside corner of your eye to keep the medicine from draining out. Do not rub your eyes.

To keep from contaminating the medicine, do not let the tip of the dropper touch your eye or any other surface. After use, wipe the tip with a clean tissue. Put the cap on tightly and store the medicine away from heat and bright light. Do not use the medicine if it becomes discolored.

If you are using more than one type of eye drop, ask your healthcare provider which one to use first. Do not use other eye drops for 5 to 10 minutes before or after you use this medicine.

If you wear contact lenses:

  • Wait at least 10 minutes after applying the drops before inserting your contact lenses
  • Do not wear contact lenses if your eyes are red.
  • Do not use this medicine to treat contact lens related irritation.

This medicine is for use in the eyes only. Do not take it by mouth.

How to take azelastine

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

Warnings and Precautions

In clinical trials, the occurrence of somnolence has been reported in some patients taking Azelastine hydrochloride nasal spray [see Adverse Reactions (6.1)]. Patients should be cautioned against engaging in hazardous occupations requiring complete mental alertness and motor coordination such as operating machinery or driving a motor vehicle after administration of Azelastine hydrochloride nasal spray. Concurrent use of Azelastine hydrochloride nasal spray with alcohol or other central nervous system depressants should be avoided because additional reductions in alertness and additional impairment of central nervous system performance may occur.