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Apixaban Nursing Implications

Apixaban Nursing Implications

What Is Eliquis (Apixaban)?

Eliquis is the brand name of the prescription medicine apixaban, which is used to prevent strokes and blood clots in people with atrial fibrillation (a condition characterized by an irregular heartbeat).

This medicine is also given to treat or reduce the risk of developing deep vein thrombosis (DVT; a blood clot that usually develops in the leg) and pulmonary embolism (PE; a blood clot in the lung).

In addition, Eliquis may be prescribed after hip or knee replacement surgery to help prevent DVT or PE.


Do not stop taking apixaban without talking to your doctor. Stopping apixaban when you are not supposed to may raise the chance of blood clots. This includes stroke in certain people. You may need to stop apixaban before certain types of dental or health care. Your doctor will tell you when to start taking it again. Follow what your doctor tells you closely.

People who have any type of spinal or epidural procedure are more likely to have bleeding problems around the spine when already on this drug. This bleeding rarely happens, but can lead to not being able to move body (paralysis) long-term or paralysis that will not go away. The risk is raised in people who have problems with their spine, a certain type of epidural catheter, or have had spinal surgery. The risk is also raised in people who take any other drugs that may affect how the blood clots like blood-thinner drugs (like warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs). Talk with the doctor.

Eliquis Coupons and Prices

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Side Effects

Tell your doctor immediately if you experience any of the symptoms listed in the Eliquis Warnings section above, or the following serious side effects:

  • Easy bruising
  • Unusual bleeding or bleeding that won't stop, including nosebleeds and bleeding gums
  • Heavy menstrual periods
  • Pink, brown, or red urine
  • Black or bloody stools
  • Coughing up blood, or vomit that looks like coffee grounds
  • Trouble breathing or wheezing
  • Severe headache
  • Dizziness or feeling like you might pass out
  • Severe weakness
  • Rash

How is this medicine (Apixaban) best taken?

Use apixaban as ordered by your doctor. Read all information given to you. Follow all instructions closely.

Take with or without food.

If you have trouble swallowing apixaban, it can be crushed and mixed in water, apple juice, or applesauce. If you crush and mix apixaban, take it within 4 hours of mixing.

To gain the most benefit, do not miss doses.

Keep taking apixaban as you have been told by your doctor or other health care provider, even if you feel well.

Those who have feeding tubes may use apixaban. Use as you have been told. Flush the feeding tube after apixaban is given.


Tell your doctor about all prescription, nonprescription, illegal, recreational, herbal, nutritional, or dietary drugs you're taking, especially those listed in the Eliquis Warnings section above, and the following:

  • Biaxin or Prevpac (clarithromycin)
  • Carbatrol, Epitol, Equetro, Tegretol, or Teril (carbamazepine)
  • Dilantin or Phenytek (phenytoin)
  • Nizoral (ketoconazole)
  • Norvir or Kaletra (ritonavir)
  • Onmel or Sporanox (itraconazole)
  • Rifadin, Rimactane, Rifadin, or Rifater

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