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Apixaban Dose In Elderly

Apixaban Dose In Elderly

What is apixaban?

Apixaban blocks the activity of certain clotting substances in the blood.

Apixaban is used to lower the risk of stroke caused by a blood clot in people with a heart rhythm disorder called atrial fibrillation.

Apixaban is also used after hip or knee replacement surgery to prevent a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism).

How should I take apixaban?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take apixaban with or without food.

If you cannot swallow a tablet whole, crush and mix it with water, apple juice, or a spoonful of applesauce. Swallow the mixture right away without chewing. Do not save it for later use.

A crushed tablet mixture may also be given through a nasogastric (NG) feeding tube. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

What happens if I miss a dose?

Take the missed dose on the same day you remember it. Take your next dose at the regular time and stay on your twice-daily schedule. Do not take two doses at one time.

Get your prescription refilled before you run out of medicine completely.

What happens if I overdose?

Seek emergency medical attention or call the Poison.

side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Also seek emergency medical attention if you have symptoms of a spinal blood clot: back pain, numbness or muscle weakness in your lower body, or loss of bladder or bowel control.

  • Call your doctor at once if you have:
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), bleeding from wounds or needle injections, any bleeding that will not stop;
  • heavy menstrual periods;
  • headache, dizziness, weakness, feeling like you might pass out;
  • urine that looks red, pink, or brown; or
  • black or bloody stools, coughing up blood or vomit that looks like coffee grounds.

Conclusions

This analysis of the AVERROES trial demonstrates that older patients with AF, even the very elderly, derive benefit from apixaban. Increased age does not increase the risk of bleeding of apixaban when compared to aspirin; and in the very elderly there may even be a benefit of apixaban over aspirin for intracranial haemorrhage. Based on the present analysis, it difficult to justify the use of aspirin in elderly patients with AF, if apixaban is available.

Know More About This Medicine and Buy Now :  MedyPharma.com

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