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Anastrozole Steroid

Anastrozole Steroid

Anastrozole

The hormonal dependency of  breast cancer was first recognized more than a century ago. Although it has yet to be proven that estrogen is directly responsible for the initiation of breast tumors, it is clear from epidemiologic evidence, from "prevention" studies using the antiestrogen tamoxifen (Nolvadex), and from the clinical impact of hormonal manipulation that estrogen is a significant factor in the maintenance and progression of established tumors.

Estrogen is produced by aromatization of androgens. In premenopausal women, androgens are synthesized from cholesterol by the adrenals and the ovaries in roughly equivalent proportions. Approximately 60% of estrogens in premenopausal women are synthesized in the aromatase-rich cytoplasm of the granulosa cells of the ovaries. Aromatization by the cycling ovary is regulated by follicle-stimulating hormone that is regulated, in turn, by estrogen in a negative feedback loop. The remaining 40% of estrogens in premenopausal women are synthesized in the peripheral tissues, particularly in fat.

Arimidex vs Nolvadex

The main advantage in using arimidex over a SERM, like tamoxifen (nolvadex), is that arimidex blocks the aromatase enzyme; thereby, it prevents the production of estrogen in the first place. As a comparison, Tamoxifen will hinder the estrogen receptors from receiving the estrogen, rather than stopping production at the source. Therefore, you'll still have estrogen floating around in your body when you use a SERM.

How does anastrozole work?

Some breast cancers are stimulated to grow by the hormone oestrogen. In women who have been through the menopause, oestrogen is no longer produced by the ovaries. But some oestrogen is still made in body fat using an enzyme (a type of protein) called aromatase. Aromatase inhibitors stop this enzyme from working so there’s less oestrogen in the body.

Anastrozole will only be prescribed if your breast cancer has receptors within the cell that bind to the hormone oestrogen, known as oestrogen receptor positive or ER+ breast cancer. All breast cancers are tested for oestrogen receptors using tissue from a biopsy or after surgery. When oestrogen binds to these receptors, it can stimulate the cancer to grow.

How is anastrozole taken?

Anastrozole is a tablet (1mg) that you take once a day. It can be taken with or without food.

It’s best to take it at the same time every day. If you miss a dose, you don’t need to take an extra dose the next day as the level of drug in your body will remain high enough from the previous day. If for any reason you want to stop taking anastrozole it’s important that you talk to your specialist first. This is because not taking the drug for the recommended time means you may increase your risk of your breast cancer coming back.

Arimidex Side Effects

Side effects of arimidex virtually do not exist. In breast cancer studies, there was some bone weakness associated with arimidex use, but keep in mind it was used for years on a daily basis. For a bodybuilder, who uses a proper dose during a cycle, this is not an issue.

  • Headache
  • Hot Flashes
  • High Blood Pressure
  • Joint Pain
  • Depression (rare)
  • Nausea and or Vomiting (rare)

Arimidex Dosages

Dosages of arimidex will vary from person to person. This is why blood work is essential to finding the perfect balance. One should start out at half a mg every other day and adjust as needed for the cycle. Some AAS users will not use an AI at first but they will have it on hand just in case. This isn't always a good idea, as once you start noticing gyno or excessive water weight it could be too late to reverse. Since AAS will continue building in the body and aromatize (steroids turning into estrogen), taking arimidex at this point would be like trying to stop a car already in motion.

Know More About This Medicine and Buy Now :  MedyPharma.com

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