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Anastrozole Dosage For Trt

 Anastrozole Dosage For Trt


The purpose of this article is to outline everything that is involved when it comes to beginning Testosterone Replacement Therapy (TRT). After reading this article you should feel confident about the TRT process and what to expect along the way.

Estradiol in Men

Most men think of estrogen as exclusively a female hormone, but men also produce it. In fact, testosterone is the precursor of estradiol, an estrogen and the primary female sex hormone. Testosterone is converted into estradiol via the aromatase enzyme.

Because testosterone can be converted into estradiol, taking testosterone via testosterone replacement therapy (TRT) can potentially elevate estrogen levels. Fortunately, most men on standard TRT dosages do not experience high estradiol levels. Nevertheless, genetically predisposed men may experience symptoms associated with high levels, which may lead to certain unwanted side effects.

What are High Estradiol Levels in Men?

The definition of high estradiol levels in men varies by laboratory and type of analytical method. Unfortunately, there is also no consensus on what type of test (regular or ultrasensitive) is best.

Lab Corp uses an electro-chemiluminescence immunoassay methodology and defines high estradiol as equal to or above 42.6 pg/mL.

TRT Protocols

Now that we have figured out what service we would like to use let’s talk about what drugs you are most likely going to be taking. The protocol that I’ll be discussing is one of many possible TRT protocols but it is the most effective. I will be writing a future article comparing the different types of TRT protocols.

The 3 most common drugs that are prescribed to treat TRT are Testosterone Cypionate, Human Chorionic Gonadotropin (HCG), and Anastrozole (Arimidex). I will go into a little detail about what these drugs are, how they are administered, and how often they should be taken. There will be a future article that will go into more depth as to what these drugs actually do.

TRT Dosing and Frequency

Dosing and frequency will vary from person to person but injections are usually taken 1-2x a week and pills are taken 1-2x a week as well.

Testosterone Cypionate

Most doctors will prescribe a patient 100-200mg of testosterone cypionate to be taken every week. Some doctors will suggest to take the full dosage 1x a week or split the dosage in half and to be taken 2x a week. So for example if you are prescribed 200mg a week, you would take 100mg every 3-4 days if you are splitting the dosage into 2x a week.

Why would you want to split the dose? When you take testosterone your body’s testosterone levels will spike and then fall. This causes what’s known as the rollercoaster effect. When your testosterone levels are high you reap all of the benefits of TRT. You feel great. You have a lot of energy, your mood is elevated, sex drive is up, and overall life is good. Once the testosterone starts to wear off and your levels start to drop you will possibly start to feel like you did before taking testosterone. You may become lethargic, lose libido, and become irritable. By splitting the dosage into 2x a week you help prevent this rollercoaster effect and help keep your testosterone levels at a happy and consistent medium.

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