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For what conditions or diseases is this medication prescribed?

Anastrozole is used with other treatments, such as surgery or radiation, to treat early-stage breast cancer in women who have experienced menopause (life change, the end of menstrual periods). This medication is also used in women who have experienced menopause, as a first treatment for breast cancer that spread within the breast or to other areas of the body. This medicine is also used to treat breast cancer in women whose breast cancer has worsened after taking tamoxifen (Nolvadex). Anastrozole is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen that the body produces. This can slow or stop the growth of several types of breast cancer cells that need estrogen to grow.

What do I have to do if I forget to take a dose?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue your normal medication schedule. Do not take a double dose to make up for the one you forgot.

What are the possible side effects of this medication?

  • weakness
  • headache
  • hot flashes
  • Sweating
  • stomach ache
  • sickness
  • vomiting

Mechanism of action

It reduces the circulating levels of estradiol, by inhibiting aromatase, an enzyme that intervenes in the synthesis of estrogens from androgenic precursors.

Therapeutic indications

Tto. of advanced breast cancer with hormonal receptor + in postmenopausal women. Tto. adjuvant of postmenopausal women who present with invasive breast cancer in initial stages with hormonal receptor +. Tto. adjuvant of postmenopausal women who have invasive breast cancer in the early stages with hormone receptor +, who have received tto. adjuvant with tamoxifen for a period of 2 to 3 years.

How should I store or dispose of this medicine?

Keep this product in its original container, perfectly closed and out of the reach of children. Store it at room temperature and in a place away from excess heat and humidity (never in the bathroom).

Warnings and precautions

In patients whose postmenopausal status is unclear, an assessment of LH, FSH and / or estradiol levels must first be performed to clearly establish postmenopausal status before treatment is initiated.

By decreasing estrogen levels, reduction of bone density can occur. To investigate the bone mineral density in patients with osteoporosis or more likely, before the start of treatment and at regular intervals thereafter. Start and monitor prophylaxis or treatment of osteoporosis if necessary.

Be cautious in severe renal and / or hepatic impairment because anastrozole has not been studied.

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