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Alogliptin Pioglitazone

Alogliptin Pioglitazone

What Is Alogliptin-Pioglitazone?

Alogliptin and pioglitazone are oral diabetes medicines that helps control blood sugar levels.

Alogliptin and pioglitazone is a combination medicine for people with type 2 diabetes. This medicine is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes.

Alogliptin and pioglitazone may also be used for purposes not listed in this medication guide.

You should not use this medicine if you have severe or uncontrolled heart failure, active bladder cancer, or diabetic ketoacidosis (call your doctor for treatment with insulin). Alogliptin and pioglitazone is not for treating type 1 diabetes.

This medicine can cause or worsen congestive heart failure. Call your doctor at once if you have shortness of breath (even with mild exertion), swelling, or rapid weight gain.

Uses

This combination medication is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.

This product contains 2 medications: alogliptin and pioglitazone. Alogliptin works by increasing levels of natural substances called incretins. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also decrease the amount of sugar your liver makes. Pioglitazone works by helping to restore your body's proper response to insulin.

How to use Alogliptin-Pioglitazone

Read the Medication Guide provided by your pharmacist before you start using alogliptin/pioglitazone and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually once daily with or without food. The manufacturer directs not to split, break, or cut the tablet before taking it. However, many similar drugs (immediate-release tablets) can be split, broken, or cut. Follow your doctor's directions on how to take this medication.

The dosage is based on your medical condition and response to treatment. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Carefully follow your diabetes management plan, including medications, diet, and exercise.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Other medications can affect the removal of this medication from your body, which may affect how alogliptin/pioglitazone works. Examples include gemfibrozil, rifamycins (such as rifampin/rifabutin), among others.

Precautions

Before taking this medication, tell your doctor or pharmacist if you are allergic to alogliptin or pioglitazone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bladder cancer, heart problems (such as heart failure, chest pain), kidney disease, liver problems, fluid in your lungs, a certain eye problem (macular edema), disease of the pancreas (pancreatitis), stones in your gallbladder (gallstones), swelling (edema).

You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely.

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