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Allopurinol 300Mg

allopurinol 300mg

What Is Allopurinol (Zyloprim)?

Zyloprim is the brand name of the drug allopurinol, which is used to treat gout, high levels of uric acid in the body (often caused by certain cancers and cancer treatments), and kidney stones.

The medication may also be used to treat seizures, infections, and pain caused by pancreas disease. It is sometimes used to improve survival after bypass surgery, prevent rejection of kidney transplants, or reduce ulcer relapses.

Allopurinol is a type of medication called a xanthine oxidase inhibitor. It works by reducing the production of uric acid in the body. It comes in the form of an oral tablet.

Uses

Allopurinol is used to treat gout and certain types of kidney stones. It is also used to prevent increased uric acid levels in patients receiving cancer chemotherapy. These patients can have increased uric acid levels due to release of uric acid from the dying cancer cells. Allopurinol works by reducing the amount of uric acid made by the body. Increased uric acid levels can cause gout and kidney problems.

Allopurinol Side Effects

  • Vomiting
  • Diarrhea
  • Drowsiness
  • Headache
  • Muscle pain
  • Changes in sense or taste
  • Fever, sore throat, and headache with a severe blistering, peeling and red skin rash
  • Any sign of skin rash, no matter how mild
  • Nausea, upper stomach pain, itching, loss of appetite, weight loss, dark urine, clay-colored stools, jaundice
  • Pain or bleeding when urinating
  • Urinating less frequently or not at all
  • Joint pain or flu symptoms
  • Easy bruising, unusual bleeding, or purple or red pinpoint spots under the skin
  • Severe tingling, numbness, pain, or muscle weakness

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Important warnings

  • Severe skin rash: This drug may cause a severe, life-threatening skin rash. If you have itchiness, trouble breathing, or swelling of your face or throat, stop taking this drug and call your doctor right away.
  • Liver injury: This drug may cause changes in liver function test results and liver failure. This may be fatal. If you develop liver problems, your doctor may have you stop taking allopurinol.
  • Drowsiness: This drug can cause drowsiness. You shouldn’t drive, use machinery, or do other tasks that require alertness until you know how it affects you.
  • Fluid intake: You should drink at least 3.4 liters (14 cups) of fluids each day. This will help you urinate at least 2 liters (2 quarts) per day. This can help prevent uric acid crystals from forming and blocking your urine flow. Ask your doctor how to measure how much you urinate.

Who should NOT take this medication?

Do not take this medication if you:

  • are allergic to allopurinol or any ingredients of this medication
  • have previously developed a severe reaction to allopurinol or any ingredients of this medication
  • are a child (except to treat high levels of uric acid caused by cancer)
  • are a nursing mother (except to treat high levels of uric acid caused by cancer)

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