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Allopurinol 300

Allopurinol 300

What Is Allopurinol (Zyloprim)?

Zyloprim is the brand name of the drug allopurinol, which is used to treat gout, high levels of uric acid in the body (often caused by certain cancers and cancer treatments), and kidney stones.

The medication may also be used to treat seizures, infections, and pain caused by pancreas disease. It is sometimes used to improve survival after bypass surgery, prevent rejection of kidney transplants, or reduce ulcer relapses.

Allopurinol is a type of medication called a xanthine oxidase inhibitor. It works by reducing the production of uric acid in the body. It comes in the form of an oral tablet.

Important Information

You should not use allopurinol if you have ever had a serious allergic reaction to it. Stop taking the medicine and call your doctor at once if you have any signs of skin rash, no matter how mild.

Allopurinol can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Visit your doctor regularly.

Avoid drinking alcohol. It can make your condition worse. Allopurinol may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Before taking this medicine

You should not take allopurinol if you are allergic to it.

To make sure allopurinol is safe for you, tell your doctor if you have ever had:

  • kidney disease;
  • liver disease;
  • diabetes;
  • congestive heart failure;
  • high blood pressure; or
  • if you are receiving chemotherapy.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

How should I take allopurinol?

Take allopurinol exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

Take each dose with a full glass of water. To reduce your risk of kidney stones forming, drink 8 to 10 full glasses of fluid every day, unless your doctor tells you otherwise.

Take with food if allopurinol upsets your stomach.

You may have gout attacks more often when you first start taking allopurinol. Your doctor may recommend other gout medication to take at this time. Keep using your medication as directed and tell your doctor if your symptoms do not improve after 6 weeks of treatment.

You may need to follow a special diet while using allopurinol. Follow all instructions of your doctor or dietitian. Learn about the foods to eat or avoid to help control your condition.

Store at room temperature away from moisture and heat.

Important warnings

Severe skin rash: This drug may cause a severe, life-threatening skin rash. If you have itchiness, trouble breathing, or swelling of your face or throat, stop taking this drug and call your doctor right away.

Liver injury: This drug may cause changes in liver function test results and liver failure. This may be fatal. If you develop liver problems, your doctor may have you stop taking allopurinol.

Drowsiness: This drug can cause drowsiness. You shouldn’t drive, use machinery, or do other tasks that require alertness until you know how it affects you.

Fluid intake: You should drink at least 3.4 liters (14 cups) of fluids each day. This will help you urinate at least 2 liters (2 quarts) per day. This can help prevent uric acid crystals from forming and blocking your urine flow. Ask your doctor how to measure how much you urinate.

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