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Acarbose Dosage

Acarbose Dosage

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description - Consumption of alcohol may cause an increase or decrease in blood glucose levels.The mechanism involves inhibition of gluconeogenesis and the counter-regulatory response to hypoglycemia.

Instructions - Consumption of alcohol is not recommended in the patients with diabetes due to increase in the risk of altered blood glucose levels. Frequent monitoring of blood glucose levels is necessary and proper diet should be maintained for better diabetic control.

Why it’s used

Acarbose is used to treat type 2 diabetes. It helps lower your blood sugar together with diet and exercise.

How it works

Acarbose belongs to a class of drugs called alpha-glucosidase inhibitors. It works by slowing the action of certain enzymes that break food down into sugars. This slows down digestion of carbohydrates to keep your blood sugar from rising very high after you eat.

Contraindications / Precautions

General Information

When patients with diabetes, who are taking acarbose, are exposed to stress (e.g., trauma, fever, infection, or surgery), a temporary loss of control of blood glucose can occur. At such times, temporary insulin therapy may be necessary.

 Monitoring of glycemic control with urine glucose tests and the 1,5 Anhydroglucitol assay (1,5-AG assay) is not recommended in patients receiving acarbose. Use of urine glucose tests will result in positive urine glucose tests and measurements of 1,5-AG are unreliable. Use alternative methods to monitor glycemic control.

Diabetic ketoacidosis

Acarbose does not reverse any of the pathophysiologic abnormalities of diabetes mellitus. Therefore it should not be used as monotherapy in type 1 diabetes. Acarbose is not an effective treatment of diabetic ketoacidosis.

Hypoglycemia

Should mild to moderate hypoglycemia occur in a patient on acarbose (in combination with other hypoglycemic medications); oral glucose (dextrose) should be used to treat the episode. The hydrolysis of sucrose (cane sugar) to fructose and glucose is inhibited by acarbose and thus products containing sucrose are unsuitable for the rapid correction of hypoglycemia. Patients should be aware of the need to have a readily available source of glucose (dextrose, d-glucose) to treat hypoglycemic episodes. In severe hypoglycemia, intravenous dextrose or glucagon injections may be needed.

side effects

your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

Allergic skin reaction. Symptoms may include:

  • rash
  • redness
  • swelling of your skin

Liver problems. Symptoms may include:

  • yellowing of the whites of your eyes or skin
  • stomach swelling
  • pain in the upper right portion of your stomach

warnings

Pneumatosis cystoides intestinalis warning: These are gas-filled cysts on the wall of your intestines. They are a rare but serious complication of using acarbose. Symptoms include diarrhea, mucus discharge, rectal bleeding, and constipation. You need to let your doctor know immediately if you experience these symptoms.

Allergic skin reaction warning: In rare cases, using acarbose can cause an allergic skin reaction. Symptoms include rash, redness, and swelling.

Liver problems warning: Rarely, acarbose can cause liver damage. Symptoms can include yellowing of the whites of your eyes or skin, stomach swelling, or pain in the upper right portion of your stomach.

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