Abamune L

Abamune L tablets contain the active ingredients, abacavir 600mg and lamivudine, which are nucleoside reverse transcriptase inhibitors. Reverse transcriptase is a component of HIV required to infect cells so that more virus can be produced, however abacavir and lamivudine prevent transcriptase from functioning properly. These tablets also contain the following inactive ingredients: magnesium stearate, microcrystalline cellulose, sodium starch glycollate.

What is Abamune -L Tablet?

This Tablet is an antiviral medicine which is used alone or in combination with other medicines to treat human immunodeficiency virus (HIV) infection.

Abamune L medicine is not a cure for HIV. It only prevents the virus from multiplying in your body. Monitoring of liver function and blood glucose levels is necessary while receiving this medicine.

How To Take Abamune -L Tablet?

Abacavir comes as a tablet and a liquid to take by mouth. It is usually taken one or two times a day. Take it exactly as directed by your doctor.

Do not take more or less than instructed by your doctor.

Swallow the solution with some water. Abacavir must be taken regularly for it to work well. Do not stop taking Abacavir unless instructed by your doctor. If Abacavir is stopped suddenly, your condition may get worse and become harder to treat.

If you have stopped taking Abacavir for a few days or have previously been told to stop Abacavir, DO NOT restart Abacavir without first consulting your doctor.

Mechanism Action of Abamune -L?

The two medications abacavir and lamivudine combined together help prevent HIV from reproducing. The HIV virus is responsible for acquired immune deficiency syndrome as HIV infection destroys CD4 (T) cells, which are important to the body’s immune system.

The immune system is what helps fight infections. Abamune L tablets do not cure AIDS or destroy the HIV virus, but rather delay further damage to the immune system by stopping production of new viruses. Abamune tablets do not reduce the risk of passing infection to others.

You must continue to take precautions to prevent Abamune L from happening as the HIV virus can still be passed on by sexual activity or by contamination with infected blood.

Instruction for Abamune -L

Take Abamune – L Tablet exactly as instructed by the doctor. Do not take in larger or smaller quantities than recommended.

Ensure that proper hygiene measures are adopted. Complete the course of treatment to prevent the spread of the infection.

Close monitoring of liver function and blood glucose levels is necessary while receiving Abamune L medicine.

Drug interaction of Abamune -L

Interaction with Alcohol

• Description – N/A
• Instructions – Consumption of alcohol is not recommended during treatment with Abamune L medicine due to the increased risk of severe liver damage.

Interaction with Medicine

• Epirubicin
• Ribavirin

Side Effects of Abamune -L

• toxic epidermal necrolysis
• increased gamma glutamyl transferase
• Stevens- Johnson syndrome
• myocardial infarction
• cough
• gastritis
• mild elevation of blood glucose
• headache
• nausea
• abdominal pain
• diarrhea
• vomiting
• anemia
• thrombocytopenia
• neutropenia
• altered liver function tests
• CPK elevations
• pharyngitis
• pancreatitis
• body fat redistribution
• sleep disorders
• dyspnoea
• lactic acidosis
• hepatomegaly with steatosis

Warning And Precaution of Abamune -L tablet

You may take Abacavir with or without food. Try to take it at the same time each day. If you have been given Abacavir tablets, swallow it whole with a glass of water. If you have problems swallowing the tablet, you can crush it. Mix the crushed tablet with a small amount of food or drink. Swallow it immediately after mixing, do not leave it exposed to the air for too long.

Ensure that you have taken all of the crushed tablet. Use additional food or drink to wash down any remainders of the crushed tablet, if necessary.  Let your doctor know if you have problems swallowing the tablet. He may be able to recommend an alternative, such as an oral solution (a liquid). If you have been given Abacavir oral solution, use the dropper or measuring spoon provided to measure out your prescribed dose.

Pregnancy – This medicine is recommended for use in pregnant women only if necessary. All the risks and benefits should be discussed with the doctor before taking Abamune L medicine.

Diabetes – Abamune – L Tablet may alter the blood glucose levels and may also increase the risk of new-onset diabetes mellitus. Close monitoring of blood glucose levels is necessary while receiving this medicine.

Breast-feeding – Abamune L medicine is recommended for use in breastfeeding women only in life-threatening conditions. The risks and benefits should be discussed with the doctor before taking Abamune L medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.

Fat Redistribution – This Tablet may cause fat gain or fat loss from the body. Abamune L may result in peripheral wasting, facial wasting, breast enlargement, and Cushingoid appearance. Close monitoring of body weight and body fat distribution is necessary while receiving this medicine. Any changes in the body should be informed to the doctor on priority.

Uses of Abamune -L

Abamune -L Tablet is used to treat HIV-positive individuals. It is used along with other HIV medication to try and control HIV infection.

It functions by decreasing the amount of HIV in your body, and hence, helps in reducing complications like the chances of infection. Abamune L way, it increases the quality of your life.

However, keep in mind that Abamune L Tablet is not in any way a cure for HIV.

Storage of Abamune -L

It is important you keep Abamune L medication safely out of reach of children. Keep Abamune tablets stored in a cool, dry place below 25°C.